Characterization of Phenotype and Genotype of Early Onset Enteropathies

NCT02614911 · tracked via the Priya Life Science France tracker

Sponsor

Imagine Institute

Phase

Observational

Started

2014-06-16

Last updated

2025-04-30

Condition(s) studied

Inflammatory Bowel Disease

Investigational drug(s) / intervention(s)

Biological sampling

Biological sampling: Biological sampling including blood, feces, biopsies...

Study summary

This study has been set up in order to characterize phenotypes and genotypes of patients with early onset enteropathies.

In that goal, Investigators will collect biological samples (mainly blood) of patients suffering from early onset enteropathies and their healthy relatives.

Eligibility

Sex

ALL

Min age

—

Max age

—

Healthy volunteers

Accepted

Main Inclusion Criteria: * Severe chronic enteropathy * Patients developing their first symptoms within the first 6 years of life and, in priority within the first two years of life, or patients with a disease of later onset, in case of a familial history suggestive of inherited mutations notably in families comprising several affected members * OR : Be a patient's relative, even if presenting with enteropathy of later onset. Main Exclusion Criteria: * Subject having participated to any therapeutical clinical study in the 30 days preceding the inclusion in this study,

Primary outcome measure(s)

Increasing the current rate (20%) of genetic characterization of early onset entheropathies — 40 years
Currently, around 20% of early onset entheropathies are genetically characterized. Investigators want to increase this rate via this research protocol. Our long term objective is to characterize phenotypes and genotypes of patients with early onset enteropathies.

Trial sites (12)

Facility	City	Region	Status
Centre Hospitalier Pellegrin-Enfants	Bordeaux	France	Recruiting
Hôpital pédiatrique de Lyon	Bron	France	Recruiting
Hôpital Jeanne de Flandre, CHRU de Lille	Lille	France	Recruiting
Hôpital d'enfants de la Timone	Marseille	France	Recruiting
Hôpital Saint Antoine	Paris	France	Recruiting
Necker - Enfants Malades Hospital	Paris	France	Recruiting
Hôpital Robert Debré	Paris	France	Recruiting
Hôpital Trousseau	Paris	France	Recruiting
Hôpital Sud	Rennes	France	Recruiting
CHU Hautepierre	Strasbourg	France	Not Yet Recruiting
Hôpital des Enfants	Toulouse	France	Recruiting
Hôpital Clocheville, CHU de Tours	Tours	France	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT02614911 on ClinicalTrials.gov ↗ ← All trials in France