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Clinical Trials in Egypt / NCT07675330
Starting soon Not applicable

Oxymetazoline Versus Sodium Hypochlorite as Hemostatic Agents in MTA Pulpotomy of Primary Molars

NCT07675330 · tracked via the Priya Life Science Egypt tracker
Sponsor
Cairo University
Phase
Not applicable
Started
2026-08
Last updated
2026-06-30

Condition(s) studied

Pulp Disease, DentalPulp Therapy in Primary MolarsPulpitis - ReversiblePulp InflammationVital Pulp TherapiesCarious Exposure of PulpPrimary Molar ToothPrimary Molar Pulpotomy

Investigational drug(s) / intervention(s)

Oxymetazoline 0.05% nasal solutionSodium Hypochlorite Solution

Oxymetazoline 0.05% nasal solution: Using 1 drop (\~0.05 mL) of 0.05% OXY (Normifrin Nasal spray, MUP, Egypt, and generic equivalents) delivered through a micro- brush or a small cotton pellet over pulp stumps to achieve hemostasis.

Sodium Hypochlorite Solution: Compression of a sterile cotton pellet soaked in 5% NaOCl over the pulpal stumps for 5 min

Study summary

This study aims to evaluate clinical and radiographic success of oxymetazoline versus sodium hypochlorite as hemostatic agents in MTA pulpotomy of primary molars.

Eligibility

Sex
ALL
Min age
4 Years
Max age
8 Years
Healthy volunteers
No
Inclusion Criteria: • Patients: Egyptian children with carious mandibular primary molars aged 4-8 years. • Teeth: Restorable mandibular primary molars with no clinical signs or symptoms of irreversible pulpitis. • Pre-operative Radiograph: No radiographic signs of internal or external root resorption and no furcation or periapical radiolucencies. \- Exclusion Criteria: * • Patients: 1. Uncooperative children. 2. Medically compromised children. 3. Patients whose parents refuse to participate or refuse to sign the informed consent. * Teeth: <!-- --> 1. Previously accessed molars. 2. Mobile primary molars. 3. Presence of sinus tract or pain on percussion.

Primary outcome measure(s)

  • Clinical Success. — Clinical evaluation will be performed at 1,3 &6 months postoperatively
    •Spontaneous pain: will be evaluated by asking the patient and/or guardian. Unit of measurement: Binary.
  • clinical success — Clinical evaluation will be performed at 1,3& 6 months postoperatively.
    Pain to percussion: will be tested through percussion test (using the back of the dental mirror). Unit of measurement: Binary
  • Clinical success: — Clinical evaluation will be performed at 1,3&6 months postoperatively.
    • Sinus or fistula: will be evaluated through visual examination. Unit of measurement: Binary (yes or No)
  • Clinical success — Clinical evaluation will be performed at 1,3&6 months postoperatively.
    Pathologic mobility: will be evaluated by mobility test (pressure using the ends of two dental mirrors.) Unit of measurement: Binary (yes or No)

Trial sites (1)

FacilityCityRegionStatus
Faculty of dentistry, Cairo University. Cairo Egypt

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The Antimicrobial Potential of Diclofenac Sodium as an Intracanal Medicament Recruiting
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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07675330 on ClinicalTrials.gov ↗ ← All trials in Egypt