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Clinical Trials in Egypt / NCT07657286
Recruiting Not applicable

Inflammatory Cytokines and Oxidative Stress Biomarkers in Diabetic Chronic Kidney Disease Patients

NCT07657286 · tracked via the Priya Life Science Egypt tracker
Sponsor
Badr University
Phase
Not applicable
Started
2026-06-07
Last updated
2026-06-18

Condition(s) studied

Chronic Kidney DiseaseDiabetes

Investigational drug(s) / intervention(s)

aerobic treadmill exercises

aerobic treadmill exercises: diet (1200 kcal/day)

Study summary

This research intends to analyze how a 12-week adjustment in lifestyle influences inflammatory cytokines and oxidative stress indicators in overweight individuals diagnosed with type 2 diabetes and moderate CKD

Eligibility

Sex
ALL
Min age
36 Years
Max age
58 Years
Healthy volunteers
No
Inclusion Criteria: * sedentary lifestyle for at least three months prior to enrollment * body mass index (BMI) of 30-35 kg/m². Exclusion Criteria: * using tobacco * heart failure * coronary arteries * severe heart valve problems * pregnant * liver inflammation * kidney transplant * physical injuries restricting them from exercising * utilization of anti-inflammatory medications

Primary outcome measure(s)

  • MDA — at baseline and after 12 WEEKS
    malondialdehyde
  • GSH — at baseline and after 12 WEEKS
    Glutathione
  • GPx — at baseline and after 12 WEEKS
    Glutathione peroxidase
  • SOD — at baseline and after 12 WEEKS
    Superoxide dismutase
  • IL-6 — at baseline and after 12 WEEKS
    Interleukin-6
  • TNF-α — at baseline and after 12 WEEKS
    tumor necrosis factor alpha
  • CRP — at baseline and after 12 WEEKS
    C-reactive protein

Trial sites (1)

FacilityCityRegionStatus
Mona Mohamed Abdelkhalek Cairo Egypt Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07657286 on ClinicalTrials.gov ↗ ← All trials in Egypt