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Clinical Trials in Egypt / NCT07623330
Starting soon Observational

Use of TEE Derived Measurement vs Direct Measurement Under General Anesthesia in Assessment of Pressure Gradient in Peri Membranous Ventricular Septal Defect

NCT07623330 · tracked via the Priya Life Science Egypt tracker
Sponsor
Ain Shams University
Phase
Observational
Started
2026-05-27
Last updated
2026-06-22

Condition(s) studied

Peri Membranous Ventricular Septal Defect

Study summary

In this study, the investigators aim to compare the pressure gradient obtained by transesophageal echocardiography across the restrictive peri membranous VSD with direct catheter-based measurements of such gradient.

Eligibility

Sex
ALL
Min age
6 Months
Max age
5 Years
Healthy volunteers
No
Inclusion Criteria: * Pediatric patients (6 months to 5 years). * Patients with isolated peri-membranous VSD. * Scheduled for surgical VSD closure. Exclusion Criteria: * Refusal of legal guardians. * Patients with other types of VSD. * Patients with pulmonary vascular diseases. * Patients with unrestrictive VSD. * Recent or active upper respiratory tract infection. * Any relative or absolute contraindication for TEE.

Primary outcome measure(s)

  • Accuracy of TEE-derived pressure gradient measurement across peri membranous VSD — intraoperative
    Accuracy of TEE derived Pressure gradient in numerical value across peri membranous VSD (in Rv inflow outflow view) in comparison with direct catheter-based measurements under general anesthesia.

Trial sites (1)

FacilityCityRegionStatus
Ain Shams Cairo Abbasia

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07623330 on ClinicalTrials.gov ↗ ← All trials in Egypt