TLIP Block Versus Retrolaminar Block on Quality of Recovery After Posterior Lumbar Spine Fusion Surgery

NCT07609212 · tracked via the Priya Life Science Egypt tracker

Sponsor

Assiut University

Phase

Not applicable

Started

2026-06

Last updated

2026-05-27

Condition(s) studied

Postoperative PainSpinal Fusion SurgeryDegenerative Lumbar Spine Diseases

Investigational drug(s) / intervention(s)

Thoracolumbar interfascial plane blockRetrolaminar block

Thoracolumbar interfascial plane block: Ultrasound-guided injection of local anesthetic into the fascial plane between the multifidus and longissimus muscles at the L3 level

Retrolaminar block: Ultrasound-guided injection of local anesthetic posterior to the vertebral lamina at the L3 level.

Study summary

This prospective randomized controlled study aims to compare the effects of ultrasound-guided thoracolumbar interfascial plane (TLIP) block versus retrolaminar block on postoperative quality of recovery in patients undergoing posterior lumbar spine fusion surgery. Despite advances in surgical techniques, lumbar spine fusion is associated with significant postoperative pain, which may delay recovery and increase opioid consumption.

Recent approaches emphasize multimodal analgesia and opioid-sparing strategies, including regional anesthesia techniques. Interfascial plane blocks, such as TLIP and retrolaminar block, have gained attention due to their safety and effectiveness in targeting the dorsal rami of spinal nerves supplying the posterior spinal structures.

The primary outcome of this study is postoperative quality of recovery assessed using the Quality of Recovery-15 (QoR-15) questionnaire at 24 hours. Secondary outcomes include pain scores, opioid consumption, time to ambulation, time to oral intake, and postoperative complications.

Eligibility

Sex

ALL

Min age

18 Years

Max age

65 Years

Healthy volunteers

Inclusion Criteria: * Adult patients aged 18-65 years * Male and female patients * Scheduled for elective one- or two-level posterior lumbar instrumented fusion surgery under general anesthesia * ASA physical status I-III * BMI \< 35 kg/m² * Willing to participate and provide informed consent Exclusion Criteria: * Patient refusal to participate * Coagulopathy or anticoagulant therapy * Infection at the site of block injection * Known allergy to local anesthetics * Chronic opioid use (\>3 months) * Severe hepatic, renal, or cardiac dysfunction * Neurological deficits interfering with pain assessment * Pregnancy or lactation

Primary outcome measure(s)

Quality of Recovery-15 (QoR-15) score at 24 hours postoperatively — 24 hours postoperatively
Quality of recovery will be assessed using the Quality of Recovery-15 (QoR-15) questionnaire, a validated 15-item patient-reported outcome measure. Scores range from 0 to 150, with higher scores indicating better postoperative recovery. The primary endpoint is the QoR-15 score at 24 hours after surgery.

Trial sites (1)

Facility	City	Region	Status
Assiut University Hospitals	Asyut	Egypt

More Assiut University trials in Egypt

Combined Hystroscopic and Laparoscopic Repair of CS Scar Disorder Recruiting

The Outcome of Inserting Intercostal Tube or Pleurodesis for Malignant Pleural Effusion Starting soon

Maternal Iron Deficiency and/or Iron Deficiency Anemia to Neonatal Hemoglobin Concentration and Iron Stores Starting soon

Real-Time (TRUS) Guidance in Endoscopic Treatment of BPH Starting soon

Intraoperative Lidocaine Infusion Starting soon

Other trials for the same condition

Clinical and Radiographic Evaluation of Ridge Splitting With Simultaneous Implant Placement Covered With Concentrated Growth Factor Membranes in Narrow Alveolar Ridge Starting soon

Efficacy of Serratus Posterior Superior Intercostal Plane Block on Post-operative Pain in Cardiac Surgery. Starting soon

The Effect of Anti-inflammatory Cryoagent on the Level of Postoperative Pain in Patients With Symptomatic Irreversible Pulpitis and Apical Periodontitis. Starting soon

Evaluation of Post-operative Pain and Bacterial Load Reduction After Application of Three Intra-canal Medications (Cocoa Husk Versus Calcium Hydroxide With and Without Cocoa) in Necrotic Mandibular First Molar. Active, not recruiting

Efficacy of Preventive Ketamine on Postoperative Pain Recruiting

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07609212 on ClinicalTrials.gov ↗ ← All trials in Egypt