🇮🇪Ireland
16°C Partly Cloudy · Dublin
Live Updates
--:--:-- IST
Contributor sign in
Latest
Clinical Trials in Egypt / NCT07175298
Starting soon Not applicable

Efficacy of Serratus Posterior Superior Intercostal Plane Block on Post-operative Pain in Cardiac Surgery.

NCT07175298 · tracked via the Priya Life Science Egypt tracker
Phase
Not applicable
Started
2025-09
Last updated
2025-09-16

Condition(s) studied

Postoperative PainCardiac Surgery

Investigational drug(s) / intervention(s)

conventional opioid-based techniqueSPSIPB Group

conventional opioid-based technique: Control Group: Participants will receive general anaesthesia with a conventional opioid-based technique

SPSIPB Group: SPSIPB Group: Participants will receive an ultrasound-guided Serratus posterior superior intercostal plane block with 30 ml 0.25% bupivacaine per side pre-incision and general anaesthesia with opioid based fentanyl

Study summary

Cardiac surgery, particularly procedures involving median sternotomy, is associated with significant postoperative pain. Acute postoperative pain is severe in cardiac patients undergoing sternotomy, and pain intensity is more severe than expected. Poorly controlled pain after surgery can lead to myocardial ischemia and pulmonary infections.Regional anesthesia techniques offer a promising alternative or adjunct to systemic opioids, providing targeted pain relief with fewer systemic side effects. The Serratus Posterior Superior Intercostal Plane Block (SPSIPB) is a novel regional anesthesia technique that involves injecting local anesthetic into the fascial plane between the serratus posterior superior muscle and the intercostal muscles

Eligibility

Sex
ALL
Min age
18 Years
Max age
60 Years
Healthy volunteers
No
Inclusion Criteria: * aged 18 to 60 * both sexes * who are scheduled to have fast-tracking elective on-pump cardiac surgery through a median sternotomy, * American Society of Anesthesiologists Physical status II-III, * Ability to understand and provide informed consent Exclusion Criteria: * patients who refused to participate in the study, * who had Cognitive impairment or mental disorders, * Ages \<18 and \>60 years, * BMI \<18 and \>35, * patients with puncture site infection, * patients who documented allergy to local anesthetic drugs, * patients used to take chronic pain medications, patients who made previous sternotomy or chest surgery * patients with a history of substance abuse.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Faculty of medicine ,Alexandria university Alexandria Alexandria Governorate

More Alexandria University trials in Egypt

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07175298 on ClinicalTrials.gov ↗ ← All trials in Egypt