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Clinical Trials in Egypt / NCT07371416
Active, not recruiting Not applicable

Regenerative Root Canal Treatment of Immature Teeth Using Omega-3 Fatty Acids

NCT07371416 · tracked via the Priya Life Science Egypt tracker
Phase
Not applicable
Started
2025-10-01
Last updated
2026-01-28

Condition(s) studied

Immature Permanent Teeth With Open ApexPulp Necrosis

Investigational drug(s) / intervention(s)

Omega -3 fatty acidsCalcium Hydroxide (Ca(OH)2) →

Omega -3 fatty acids: used within the Regenerative procedures

Calcium Hydroxide (Ca(OH)2): Used as intracanal medicament

Study summary

This clinical study will be conducted to evaluate the effect of using intracanal Omega-3 Fatty acids during revascularization of necrotic immature teeth compared to the traditional induced bleeding technique.

Eligibility

Sex
ALL
Min age
6 Years
Max age
28 Years
Healthy volunteers
Accepted
Inclusion Criteria: * Patients aged between 6 and 28 years. * Systemically healthy patients with no history of systemic diseases. * Patients with necrotic immature permanent teeth due to trauma and/or caries. * Preoperative radiographic evidence of incomplete root formation. * Wide apical foramen (apical diameter ≥ 1 mm). * Thin dentinal walls on preoperative radiographs. Exclusion Criteria: * Patients with known allergy to any of the drugs used in the study. * Patients with systemic diseases or medically compromised conditions. * Grossly decayed or fractured teeth requiring post and core restorations. * Presence of draining sinus tract. * Presence of periodontal pockets. * Radiographic evidence of external or internal root resorption. * Patients with a history of major surgeries (e.g., cardiac surgery, kidney transplantation). * Patients undergoing hemodialysis.

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Mansoura University Al Mansurah Egypt

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07371416 on ClinicalTrials.gov ↗ ← All trials in Egypt