Moringa Oleifera vs Sodium Hypochlorite for Root Canal Irrigation in Nonvital Primary Molars

Condition(s) studied

Investigational drug(s) / intervention(s)

Sodium hypochlorite: sodium hypochlorite solution will be used as a root canal irrigant during pulpectomy in primary molars. A volume of 3 mL will be delivered into each canal using a syringe with a side-vented needle. Irrigation will be followed by microbial sampling for blood agar

Moringa Oleifera Leaf Extract: extract of Moringa oleifera leaves will be used as an intracanal irrigant during pulpectomy. A volume of 3 mL will be used per canal, and post-irrigation microbial samples will be analyzed using the same methods as the control group.

Study summary

This randomized clinical trial aims to evaluate and compare the antimicrobial efficacy of Moringa Oleifera leaf extract versus sodium hypochlorite as root canal irrigants in pulpectomy of nonvital primary molars in pediatric patients. The study will assess bacterial reduction using blood agar

Eligibility

Primary outcome measure(s)

• Zone of inhibition against Coagulase-Negative Staphylococci — "Day 1 (Pre- and post-irrigation samples collected during the same visit)"
  "Primary Outcome: The antimicrobial efficacy of both types of irrigants... based on the diameter of the zone of inhibition

Trial sites (1)

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