Opioid Free AnesthesiaControl group (general anesthesia)
Opioid Free Anesthesia: patients will receive opioid free anesthesia and bilateral ultrasound guided transversus abdominus plane block.
Control group (general anesthesia): patients will receive conventional general anesthesia
Study summary
This study aimed to determine the effects of Opioid-free anesthesia using dexmedetomidine and bilateral Transversus abdominis plane block on the quality of recovery, incidence of Opioid-free anesthesia, and post-operative pain and delirium in morbid obese patients undergoing gynecological surgeries.
Eligibility
Sex
FEMALE
Min age
21 Years
Max age
65 Years
Healthy volunteers
No
Inclusion Criteria:
* 50 female patients aged 21-65 years.
* Patients with a Body mass index≥ 35 kg/m2
* American society of Anesthesiology class II-III.
* Undergoing elective gynecological surgeries.
Exclusion Criteria:
* Patient refusal.
* History of allergy to local anesthetic.
* Liver or renal pathology affecting drug elimination.
* Mental dysfunction or cognitive disorders.
* Patients on chronic pain medications.
* Hypotension, bradycardia, atrioventricular block, intraventricular or sinoatrial block.
* Coagulopathy
Primary outcome measure(s)
quality of recovery on postoperative day — one day The Quality of Recovery-40 questionnaire scores. The Quality of Recovery-40 questionnaire includes five dimensions of recovery: physical comfort (12 items), emotional state (9 items), physical independence (5 items), psychological support (7 items), and pain (7 items).
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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