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Clinical Trials in Egypt / NCT03436368
Active, not recruiting Not applicable

Continuous Spinal Anesthesia in Renal Transplantation

NCT03436368 · tracked via the Priya Life Science Egypt tracker
Phase
Not applicable
Started
2018-02-20
Last updated
2026-01-12

Condition(s) studied

Renal Failure ChronicTransplant;Failure,KidneyAnesthesia

Investigational drug(s) / intervention(s)

Continuous spinal anesthesiaGeneral anesthesia

Continuous spinal anesthesia: Continuous spinal anesthesia will be performed for patients of the CSA group at the L3-L4 intervertebral space using Spinocath (B. Braun, Melsungen, Germany). After the cerebrospinal fluid is aspirated, 7.5 mg hyperbaric Bupivacaine 0.5% (1.5 ml) together with 25 micrograms Fentanyl (0.5 ml) will be injected intra-thecally. Supplemental injections will be given in aliquots of 5 mg hyperbaric Bupivacaine 0.5% (1 ml) if the sensory block is lower or reseeds, during surgery, below T6 dermatome.

General anesthesia: Anesthesia will be induced with intra-venous administration of Fentanyl (2 micrograms/kg), Ptopofol (1-2 mg/kg) and Atracurium (0.5 mg/kg). Maintenance will be achieved with 0.8-1.5% Isoflurane in an O2 / air mixture, an Atracurium infusion at 0.5 mg/kg/hr and a Fentanyl infusion at 1 micrograms/kg/hr.

Study summary

Renal transplantation is now recognized as a treatment of choice for patients with end-stage renal disease. An adequate anesthetic technique should achieve hemodynamic stability and enhance perfusion of the transplanted kidney. The aim of this study is to assess the use \& effects of continuous spinal anesthesia for kidney transplantation recipients, compared with balanced general anesthesia.

Eligibility

Sex
ALL
Min age
18 Years
Max age
70 Years
Healthy volunteers
No
Inclusion Criteria: * ASA class III or IV * End-stage renal disease * Renal transplantation candidate patients Exclusion Criteria: * Any condition contra-indicating regional anesthesia * Coagulopathy * Allergic to any of the drugs used during the procedure

Primary outcome measure(s)

Trial sites (1)

FacilityCityRegionStatus
Kasr Al-Ainy Hospital, Cairo University Cairo Egypt

More Nazmy Edward Seif trials in Egypt

Other trials for the same condition

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT03436368 on ClinicalTrials.gov ↗ ← All trials in Egypt