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Clinical Trials in Egypt / NCT06859320
Active, not recruiting Not applicable

Outcomes Of Laparoscopic Sleeve Gastrectomy In Patients With Hypothyroidism And Depression

NCT06859320 · tracked via the Priya Life Science Egypt tracker
Sponsor
Zagazig University
Phase
Not applicable
Started
2025-03-01
Last updated
2025-08-14

Condition(s) studied

Obesity and Obesity-related Medical Conditions

Investigational drug(s) / intervention(s)

laparoscopic sleeve gastrectomy

laparoscopic sleeve gastrectomy: laparoscopic sleeve gastrectomy is one of the popular bariatric surgeries known for weight reduction

Study summary

Sleeve gastrectomy (SG) continues to be one of the most popular bariatric procedures all over the world. It has been established that obesity is a predisposing factor for several comorbidities, including life-threatening conditions. Many studies have discussed the impact of sleeve gastrectomy on TSH level. But, since most obese patients have some sort of depression, we will try to study the impact of sleeve gastrectomy, depression and hypothyroidism on each other.

Eligibility

Sex
ALL
Min age
18 Years
Max age
60 Years
Healthy volunteers
No
Inclusion Criteria: * obese patients with depression and hypothyroidism controlled by medical treatment candidate for sleeve gastrectomy Exclusion Criteria: * patients less than 18 or above 60 * other psychiatric or medical disorders. * patients not fit for surgery * un controlled patients

Primary outcome measure(s)

  • thyroid function tests — from one day to one year after surgery
    TSH,T3,T4 are measured pre and post operative
  • depression — from one day to one year after surgery
    depression status is compared pre-operative and post-operative using depression questionnaire (PHQ-9)( patient health questionnaire-9)
  • weight — from one day to one year after surgery
    weight of the patient will be measured in Kg using weight scale
  • dose of thyroid replacement therapy — monthly from one day to one year post surgery.
    the dose of L-thyroxin is monitored in microgrames
  • gasteric leakage — from one day to 1 week post-surgery
    leakage after surgery from staple line measured in ml in the drain
  • wound infection — from one day to 2 weeks post-surgery
    wound infection will be identified by pus in the drain or in the wound

Trial sites (2)

FacilityCityRegionStatus
Faculty of Medicine Zagazig Sharqia Province
Zagazig University Hospitals Zagazig Egypt

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Other trials for the same condition

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06859320 on ClinicalTrials.gov ↗ ← All trials in Egypt