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Starting soon Not applicable

Comparison Between Combined Biceps Femoris Short Head Block and Adductor Canal Block Versus Genicular Nerve Block

NCT07418307 · tracked via the Priya Life Science Egypt tracker
Phase
Not applicable
Started
2026-02-15
Last updated
2026-02-18

Condition(s) studied

Knee Arthroplasty, Total

Investigational drug(s) / intervention(s)

Combined biceps femoris short head block and adductor canal blockGenicular nerve block

Combined biceps femoris short head block and adductor canal block: Adductor Canal Block high-frequency probe will be placed transversely on the anterior thigh midpoint between inguinal crease and medial condyle (depth 3-5 cm). The needle will be advanced in-plane from lateral to medial through sartorius or vastus medialis muscle toward the femoral artery. Then (10 ml of 0.25% bupivacaine and 2 mg dexamethasone) will be injected after negative aspiration, with confirming spread around the artery without vascular puncture. Biceps femoris short head block The probe will be placed on the distal posterior thigh to visualize biceps femoris muscle near the lateral supracondylar line of the femur. The needle will be inserted to the interface between biceps femoris and femur cortex. Then (25 ml of 0.25% bupivacaine and 2 mg dexamethasone), with observing muscle lift and circumferential spread along the bone surface .

Genicular nerve block: Position the patient will be placed in supine position with the knee slightly flexed via a pillow in the popliteal fossa. Use a high-frequency linear ultrasound transducer. Superolateral genicular nerve (SLGN): the transducer will be placed coronally over lateral femoral epicondyle, with sliding proximally to femur metaphysis; identifying artery between vastus lateralis fascia and bone. Superomedial genicular nerve (SMGN): the transducer will be placed coronally over medial femoral epicondyle, proximal to adductor tubercle at femur metaphysis; artery between vastus medialis fascia and bone. Inferomedial genicular nerve (IMGN): the transducer will be placed coronally over medial tibial condyle, distal to metaphysis; artery beneath medial collateral ligament. • Inferolateral genicular nerve (ILGN, optional): the transducer will be placed coronally over lateral tibial epicondyle to fibula head; artery between collateral ligament and tibia

Study summary

The purpose of this study is to compare the analgesic outcomes (time to first analgesic request, total amount of analgesic consumption, and pain scores) following total knee arthroplasty by either combined biceps femoris short head block and adductor canal block or genicular nerve block in elderly patients.

Eligibility

Sex
ALL
Min age
65 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * patient acceptance * Physical status: ASA I, II and Ⅲ. * Body mass index (BMI): 18.5 - 35 kg/m2. * Type of operations: total knee arthroplasty. Exclusion Criteria: * Known hypersensitivity to dexamethasone or bupivacaine. * Coagulation disorders or taking drugs affect surgical hemostasis. * Patients with pre-existing neurological deficits. * Uncooperative patient or with altered mental status. * Patient with advanced cardiovascular or respiratory diseases or uncontrolled diabetes

Primary outcome measure(s)

  • Time of first rescue analgesia (naluphine) — 24 hours postoperative
    to the duration from the block to the moment when the patient first requires or requests supplemental nalbuphine due to breakthrough pain

Trial sites (1)

FacilityCityRegionStatus
Faculty of Medicine,Zagazig University Zagazig Egypt
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07418307 on ClinicalTrials.gov ↗ ← All trials in Egypt