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Clinical Trials in China / NCT07881094
Starting soon Observational

China Healthy Aging and Fitness Longitudinal Study

NCT07881094 · tracked via the Priya Life Science China tracker
Sponsor
China Institute of Sport Science
Phase
Observational
Started
2026-10-30
Last updated
2026-10-23

Condition(s) studied

Physical FitnessAging

Study summary

The China Healthy Aging and Fitness Longitudinal Study (CHALF) is a nationwide prospective observational study designed to investigate how physical activity, exercise, and physical fitness are associated with health and aging among older adults in China.

The study plans to recruit approximately 8,960 adults aged 60-79 years from 14 provinces and provincial-level regions across China. Participants will complete questionnaires about their physical activity, exercise habits, lifestyle, nutrition, and health. They will also undergo standardized physical fitness assessments and blood tests.

Participants will be followed over time to track changes in physical fitness and health. Follow-up assessments will examine how physical activity, exercise, and physical fitness are associated with physical function, chronic diseases, and other health outcomes.

The findings will help improve understanding of healthy aging and provide evidence to support physical fitness monitoring and exercise guidance for older adults in China.

Eligibility

Sex
ALL
Min age
60 Years
Max age
79 Years
Healthy volunteers
Accepted
Inclusion Criteria: 1. Adults aged 60-79 years at baseline, with valid identification documents. 2. Having resided in the selected study area for at least one year, with no plans to relocate or leave the area for an extended period within the next five years. 3. Able to independently perform basic activities of daily living and participate in basic physical activities. 4. Able to communicate clearly, understand and respond to study questionnaires, without cognitive impairment or communication difficulties. 5. Having no contraindications to exercise. 6. Willing to provide written informed consent and participate in longitudinal follow-up assessments. Exclusion Criteria: 1. Temporary residents or individuals planning to relocate from the study area. 2. Surgery or major trauma, including fractures, within the previous six months. 3. Cancer or a history of cancer treatment, including chemotherapy or radiotherapy. 4. Uncontrolled hypertension or diabetes mellitus. 5. Severe cardiovascular diseases, including symptomatic valvular heart disease, hypertrophic cardiomyopathy, unstable angina, heart failure, severe arrhythmias, or primary pulmonary hypertension. 6. Severe chronic obstructive pulmonary disease or severe osteoporosis. 7. Diagnosed Alzheimer's disease or other severe cognitive impairment. 8. Severe chronic infectious diseases, including HIV/AIDS, syphilis, or active tuberculosis.

Primary outcome measure(s)

  • All-Cause Mortality — Baseline through Year 9 (2026-2035).
    All-cause mortality will be assessed as the proportion of participants who have died from any cause during the follow-up period.
  • Disability-Free Survival Status — Baseline and annually through Year 9 (2026-2035).
    Disability-free survival status will be assessed based on participants' vital status and incident ADL disability. The proportion of participants who remain alive and free of ADL disability will be evaluated at annual follow-up visits.

Trial sites (1)

FacilityCityRegionStatus
China Institute of Sports Science Beijing Beijing Municipality

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07881094 on ClinicalTrials.gov ↗ ← All trials in China