Atrial fibrillation (AF) is a common arrhythmia in aging populations and is strongly associated with an increased risk of heart failure (HF) and adverse cardiovascular outcomes. However, early detection of HF among patients with AF remain inadequate in rural settings. This study aims to screen for HF among older adults with AF in rural China and to conduct long-term follow-up in order to observe the disease progression in patients with AF.
This study will recruit at least 2,500 elderly individuals aged between 65 and 80 years, with confirmed diagnoses of AF, residing in rural areas. Participants will undergo HF screening using NT-proBNP testing and echocardiographic assessment. Additionally, data will be collected on electrocardiographic signals, seismocardiography, voice, and demographic characteristics. Following data collection, participants will be followed up every three months to monitor the incidence and progression of HF as well as the occurrence of adverse cardiovascular events.
Eligibility
Sex
ALL
Min age
65 Years
Max age
80 Years
Healthy volunteers
No
Inclusion Criteria:
1. Permanent residents with local household registration in rural China.
2. Aged 65-80 years.
3. Electrocardiogram confirmation of AF or possession of a diagnostic certificate for AF issued by a specialist.
4. Willing to participate in HF screening.
5. Ability to understand the study procedures and provide written informed consent.
Exclusion Criteria:
1. Expected life expectancy of less than 3 months.
2. Severe renal insufficiency (Ccr \< 30ml/min) or ongoing dialysis treatment.
3. Cardiac insufficiency secondary to correctable causes, including hyperthyroid heart disease, anemic heart disease, or uncorrected congenital heart disease.
4. Indications for pacemaker implantation without having undergone implantation.
5. Chronic obstructive pulmonary disease complicated by type II respiratory failure.
6. Special populations, including patients with mental illnesses.
Primary outcome measure(s)
Composite endpoint — through study completion, an average of 3 years a composite of cardiovascular mortality, all strokes (ischemic or hemorrhagic stroke), hospitalization due to worsening of HF or acute coronary syndrome (ACS), and emergency visits due to AF
Trial sites (1)
Facility
City
Region
Status
Department of Cardiology
Taizhou
Jiangsu
Recruiting
More Jiangsu Taizhou People's Hospital trials in China
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
We use cookies to analyse site traffic and improve your experience. With your consent, we may also use cookies for advertising. You can change your choice at any time on our Cookie Policy page. See also our Privacy Policy.