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Recruiting Phase 2

A Prospective, Two-center, Single Arm Phase II Clinical Study to Evaluate Safety and Effectiveness of Ablation Therapy in the Treatment of Lung Cancer Presenting as Ground-glass Nodules

NCT04905056 · tracked via the Priya Life Science China tracker
Phase
Phase 2
Started
2021-01-01
Last updated
2021-05-27

Condition(s) studied

Progression

Investigational drug(s) / intervention(s)

Ablation therapy

Ablation therapy: Ablation therapy in the treatment of lung cancer presenting as ground-glass nodules

Study summary

A prospective, two-center, single arm phase II clinical study to evaluate safety and effectiveness of ablation therapy in the treatment of lung cancer presenting as ground-glass nodules

Eligibility

Sex
ALL
Min age
18 Years
Max age
85 Years
Healthy volunteers
No
Inclusion Criteria: 1. Aged between 18 and 85 years; 2. GGO is diagnosed by lung CT and failure to subside after 3 months (the patient having been re-examined by thin-section CT); 3. The maximum diameter of the GGO is bigger than 8mm and smaller than 3cm; 4. For single GGO: obvious progress was observed in pure GGO or the solid component of mixed ground glass nodules was more than or equal to 2 mm 5. The patients were unable to tolerate the operation for various reasons or multiple grinding glass nodules, operation can not be completely removed; or patients had received surgery in ipsilateral chest 6. The patient is able to understand and comply with the study and has provided written informed consent Exclusion Criteria: 1. Patients who participated in any drug and / or medical device clinical trials within one month before the trial 2. had severe disease conditions 3. allergy to narcotic drugs 4. had other autoimmune disease 5. dementia or cognitive impairment can't cooperate with researchers 6. any local treatment other than ablation was received within 4 weeks before the study

Primary outcome measure(s)

  • progression free survival — 1 years
    One year progression free survival after radiofrequency ablation of ground glass nodules

Trial sites (1)

FacilityCityRegionStatus
Department of Thoracic Surgery, Zhongshan Hospital, Fudan University Shanghai Shanghai Municipality Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT04905056 on ClinicalTrials.gov ↗ ← All trials in China