A Study of SHR-7367 With Anti-tumor Agents in Patients With Solid Tumors
Condition(s) studied
Investigational drug(s) / intervention(s)
SHR-7367 Injection: SHR-7367 injection.
SHR-1316 Injection: SHR-1316 injection.
Paclitaxel for Injection: Paclitaxel for injection (Albumin Bound).
Gemcitabine Hydrochloride for Injection: Gemcitabine Hydrochloride for injection.
Study summary
This study aims to evaluate the safety and preliminary efficacy of SHR-7367 in combination with antineoplastic agents in subjects with advanced solid tumors, and to determine the maximum tolerated dose (MTD) and the recommended Phase II dose (RP2D).
Eligibility
Primary outcome measure(s)
- Stage 1 (IB Period): Dose-limiting toxicity (DLT). — Up to 28 days.
- Stage 1 (IB Period): Adverse events (AEs). — About 1 year.
- Stage 1 (IB Period): Serious adverse events (SAEs). — About 1 year.
- Phase II: Investigator-assessed objective response rate (ORR). — Assessed every 6 weeks, about 1 year.
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| Tianjin Medical University Cancer Institute and Hospital | Tianjin | Tianjin Municipality | Recruiting |
More Shanghai Hengrui Pharmaceutical Co., Ltd. trials in China
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07229586 on ClinicalTrials.gov ↗ ← All trials in China