The goal of this observational study is to learn about the influence of Corona Virus Disease 2019 on obstetric outcome and offspring development.
Eligibility
Sex
FEMALE
Min age
18 Years
Max age
—
Healthy volunteers
Accepted
Inclusion Criteria:
* Conduct regular prenatal examinations in the hospital and establish a pregnancy and childbirth health manual, planning for pregnant women who are hospitalized for delivery;
* Conduct regular physical examinations in the hospital and establish a children's health manual for infants.
* Age ≥ 18 years old
Exclusion Criteria:
* Concomitant tumor related diseases;
* Individuals with severe mental disorders.
Primary outcome measure(s)
Measure the developmental outcomes of the nervous system using the Gesell Development Plan (GDS) or the 0-6-year-old Child Development Scale (DST). — From 6 months of birth to completion of the GDS measurement, the assessment is up to 6 months GDS mainly diagnoses four abilities: motor ability, object ability, speech ability, and human ability,. Thus, the development quotient of four aspects can be obtained. If the development quotient is below 65-75, it indicates serious backwardness. The DST assessment includes five functional areas: gross motor, fine motor, language, adaptability, and social behavior, to obtain developmental quotient, which is used to measure the developmental behavior of children and evaluate their level of development. A score above 130 indicates excellent performance, and a score below 70 indicates intellectual development disorder.
Pregnancy complications or comorbidities — Starting prenatal examination until discharge，the evaluation take up to 10 months Obtain relevant information from medical records. Pregnancy complications refer to non pregnancy related diseases that occur before or during pregnancy, while pregnancy complications refer to any diseases that coexist with pregnancy.
Obtain neonatal outcomes. — The evaluation period from birth to discharge is up to 1 week Obtain neonatal outcomes from neonatal records, including macrosomia, neonatal asphyxia, fetal distress, low birth weight infants, and deformed infants.
Comprehensive results of COVID-19 infection during pregnancy — Baseline data were obtained when participants were enrolled in the study and assessed for up to 1 years Through questionnaires, medical records and test sheets, The investigators can get whether the pregnant women have been infected with COVID-19 during pregnancy, the time of infection, pregnancy weeks, symptoms, etc.
Trial sites (5)
Facility
City
Region
Status
The Second Hospital of Shandong University
Jinan
Shandong
Recruiting
Jinan Maternity and Child Health Care Hospital
Jinan
China
Recruiting
Qianfoshan Hospital
Jinan
China
Recruiting
Qilu Hospital of Shandong University
Jinan
China
Recruiting
Shandong Provincial Maternity and Child Health Care Hospital
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
We use cookies to analyse site traffic and improve your experience. With your consent, we may also use cookies for advertising. You can change your choice at any time on our Cookie Policy page. See also our Privacy Policy.