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Clinical Trials in China / NCT06919484
Recruiting Observational

The Physiological Effect of RCexp on Ventilation/Perfusion Distribution

NCT06919484 · tracked via the Priya Life Science China tracker
Sponsor
Southeast University, China
Phase
Observational
Started
2025-11-30
Last updated
2025-11-26

Condition(s) studied

Acute Respiratory Distress SyndromeMechanical Ventilation

Investigational drug(s) / intervention(s)

RCexp

RCexp: patients received different RCexp

Study summary

With the exception of setting the positive end-expiratory pressure (PEEP), the expiratory phase is commonly overlooked during MV. The expiratory time constant (RCexp) plays an important role in understanding the mechanical properties of the respiratory system in patients receiving mechanical ventilation. However, it is unclear that the effect of expiratory time constant on the ventilation and perfusion distribution.

Eligibility

Sex
ALL
Min age
19 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: adult patients with ARDS receiving mechanical ventilation no more than 72 hours Exclusion Criteria: 1. age \<18 years old 2. patient undergoing legal protection 3. contra-indications to EIT (e. g. severe chest trauma or wounds) 4. pneumothorax 5. patient undergoing ECMO 6. pregnancy

Primary outcome measure(s)

  • Difference in ventilation/perfusion mismatch — 4 hours
    ventilation/perfusion mismatch is measured by EIT

Trial sites (1)

FacilityCityRegionStatus
Zhongda Hospital, School of Medicine, Southeast University Nanjing Jiangsu Recruiting

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Outcomes of Sepsis Patients in China (CHINA-SEP) Starting soon

Other trials for the same condition

Comparison of Physiological Effects of Two High-Flow Tracheal Oxygen Versus T-Piece During Spontaneous Breathing Trials Recruiting
Using Real-Time Lung Visuals to Reduce Mental Strain and Improve Diagnosis Speed Starting soon
Computed Inspiratory Muscle Pressure to Monitor Inspiratory Effort During Pressure-Targeted Assist/Control Ventilation Recruiting
Establishment and Evaluation of Prenatal Prevention and Treatment Strategy for NARDS Recruiting
Pulse Wave vs. Saline Contrast EIT for Pulmonary Perfusion in ARDS Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06919484 on ClinicalTrials.gov ↗ ← All trials in China