Clinical Trials in China / NCT06654167
Active, not recruiting
Not applicable
Acute Effects of Cold Exposure on Cognitive Function
NCT06654167 · tracked via the Priya Life Science China tracker
Condition(s) studied
Cognitive Function
Investigational drug(s) / intervention(s)
Low temperature (15℃) groupModerate temperature (22℃) group
Low temperature (15℃) group: The exposure group will be exposed to low temperature (15℃) in a chamber for about 2 hours, resting during the whole period.
Moderate temperature (22℃) group: The exposure group will be exposed to thermoneutral temperature (22℃) in a chamber for about 2 hours, resting during the whole period.
Study summary
This is a randomized controlled human exposure crossover study. Investigators aims to assess the acute effects of low-temperature exposure on cognitive function and the underlying mechanisms.
Eligibility
Inclusion Criteria:
* Living in Shanghai during the study period;
* Body mass index \> 18.5 and ≤ 28;
* right-handed;
* receiving or having received higher education;
* with the ability to read and understand Chinese smoothly.
Exclusion Criteria:
* Smoking and alcohol abuse;
* Current drug and dietary supplements intake;
* Subjects with allergic diseases, such as allergic rhinitis, allergic asthma, and atopy;
* Subjects with cardiovascular diseases, such as congenital heart disease, pulmonary heart disease, and hypertension;
* Subjects with respiratory diseases, such as asthma, chronic bronchitis, and chronic obstructive pulmonary disease;
* Subjects with chronic diseases, such as diabetes, chronic hepatitis, and kidney disease;
* Subjects who have a history of major surgery due to the cardiovascular, cerebrovascular, respiratory, or neurological diseases;
* Subjects with neurologic disorders, such as stroke, traumatic brain injury, epilepsy, and schizophrenia;
* Abnormal spirometry (FEV1 and FVC ≤ 75% of predicted and FEV1/FVC ≤ 0.65);
* Subjects with color vision disabilities.
Primary outcome measure(s)
- Results of Stroop Tests — before exposure and immediately after the exposure session
Investigators plan to measure the changes of cognitive function using Stroop Test. The time taken to complete the test could reflect cognitive function, and a shorter time means better cognitive function.
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| Department of Environmental Health, School of Public Health, Fudan University | Shanghai | Shanghai Municipality |
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Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT06654167 on ClinicalTrials.gov ↗ ← All trials in China