Effects of Repetitive Transcrannial Magnetic Stimulation on Non-Suicidal Self-Injury

Condition(s) studied

Investigational drug(s) / intervention(s)

rTMS stimulation of left M1: This study employed low-frequency repetitive transcranial magnetic stimulation (low-frequency rTMS) targeting the left primary motor cortex (M1 area). The stimulation intensity was set at 110% of the resting motor threshold (RMT). The single-session stimulation protocol was as follows: continuous stimulation at 1 Hz for 60 seconds, followed by a 5-second interval, with this cycle repeated 20 times. Thus, the total number of pulses per session was 1,200. Two sessions were administered daily, with a 40-minute interval between sessions. Treatment was conducted for 5 consecutive days per week, with 2 rest days, for a total of 2 weeks (10 treatment days). Each patient received a total of 24,000 pulses throughout the entire course. Sham stimulation utilized identical stimulation parameters as active stimulation (including frequency, intensity, duration, and number of repetitions), but employed a sham coil. This coil was identical in appearance to the active stimulation coil, producing simila

Study summary

Non-suicidal self-injury (NSSI) refers to a series of direct and consequently repeated injuries to one's body without suicidal intent. At present, it has become an important issue of mental disorders. This article focuses on the formation mechanism of NSSI and the intervention effect of rTMS on NSSI patients. At the same time, NSSI patients are collected, a treatment plan is designed to complete a two-week treatment, and the results are analyzed. The aim is to provide theoretical basis for the clinical diagnosis and treatment of NSSI, and also to provide reference for the clinical diagnosis and treatment of NSSI patients.

Eligibility

Primary outcome measure(s)

• Ottawa Self-injury Inventory — 2 weeks
  OSI was evaluated by professionally trained doctors (non experimental intervention) at baseline and two weeks after treatment to assess the effectiveness of the treatment. Comparing the differences in self harm thoughts and behaviors between the baseline period and the intervention group and the control group, p\<0.05 indicates a significant difference.
• Magnetic resonance imaging — 2 weeks

Trial sites (1)

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