Triage of Patients Presenting Beyond 24 Hours With Ischemic Stroke Due to Vertebrobasilar Artery Occlusion

Condition(s) studied

Investigational drug(s) / intervention(s)

Endovascular Therapy: Endovascular therapy, as an adjunct to standard stroke therapy, may be beneficial for a very select population of patients who present with an acute ischemic stroke and have a proven large, proximal occlusion on imaging. Endovascular therapy includes any one or more of the following: Intra-arterial thrombolytic therapy, aspiration, stent retrieval, or a combination of multiple mechanical devices.

Study summary

Endovascular thrombectomy (EVT) for posterior circulation occlusion is generally performed within a window of less than 24 hours from the time the patient was last known well (LKW). The efficacy and safety of EVT beyond the 24-hour window remain uncertain.

Eligibility

Primary outcome measure(s)

• proportion of patients with Modified ranking scale (mRS) (0-3) at 90 days — 90(±14)days
  A 0-6 scale running from perfect health without symptoms to death.

Trial sites (1)

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