Medical Imaging Screening for Posterior-circulation Ischemic Stroke

Condition(s) studied

Investigational drug(s) / intervention(s)

Endovascular Therapy: Endovascular therapy, as an adjunct to standard stroke therapy, may be beneficial for a very select population of patients who present with an acute ischemic stroke and have a proven large, proximal occlusion on imaging. Endovascular therapy includes any one or more of the following: Intra-arterial thrombolytic therapy, aspiration, stent retrieval, or a combination of multiple mechanical devices

Study summary

Patients with ischemic stroke in the posterior circulation continue to have high rates of mortality and disability, even with aggressive treatment. We wanted to evaluate preoperative imaging to screen patients with a good prognosis from mechanical embolization. We assess the degree of ischemia by defining the pons-midbrain-medulla index (PMMI) and correlate the preoperative PMMI with the clinical prognosis of postoperative patients to verify the validity of PMMI in predicting the clinical prognosis of patients with embolization.

Eligibility

Primary outcome measure(s)

• Modified ranking scale (mRS) at 90 days — 90 days
  A 0-6 scale running from perfect health without symptoms to death.

Trial sites (4)

More Tianjin Huanhu Hospital trials in China

Other trials for the same condition