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Clinical Trials in China / NCT07045987
Enrolling by invitation Observational

Exploration and Establishment of an Early Warning System for Futile Reperfusion - A I S

NCT07045987 · tracked via the Priya Life Science China tracker
Sponsor
Xijing Hospital
Phase
Observational
Started
2025-06-01
Last updated
2025-07-01

Condition(s) studied

Acute Ischemic Stroke (AIS)Endovascular ThrombectomyNeurovascular Unit- Brain Lymphatic System

Study summary

The goal of this prospective cohort registration study is to establish an early warning system for futile recanalization in acute ischemic stroke by analyzing multi-omics information to identify key regulatory nodes and target molecules in ineffective recanalization.

The core issue addressed by this research is: Identifying key regulatory nodes and target molecules closely associated with futile recanalization, revealing the interactions among the neurovascular unit, peripheral immune cells, and the brain lymphatic system, as well as developing early diagnostic biomarkers and novel diagnostic technologies for futile recanalization.

Eligibility

Sex
ALL
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: * 1\. Aged ≥18 years 2. Acute ischemic stroke confirmed by clinical and neuroimaging criteria (CT or MRI) 3. Clinical indication for thrombectomy 4. Provision of signed informed consent Exclusion Criteria: * 1\. Preexisting dementia or severe disability (modified Rankin Scale score ≥3) 2. Cerebral vascular malformations, neoplasms, abscesses, or other significant non-ischemic brain pathologies 3. Life-limiting systemic comorbidities (e.g., end-stage organ failure, metastatic malignancies) with anticipated survival \<6 months 4. Patient or legally authorized representative declined consent 5. Anticipated poor protocol adherence or loss to follow-up

Primary outcome measure(s)

  • 3-month mRS score — From enrollment to the end of treatment at 3 months

Trial sites (1)

FacilityCityRegionStatus
Luojun WANG Xi’an Shanxi

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Other trials for the same condition

Tirzepatide in Thrombectomy-Treated Acute Ischemic Stroke: A Randomized Trial Starting soon
Triage of Patients Presenting Beyond 24 Hours With Acute Ischemic Stroke Due to Large Vessel Occlusions (TRACK-LVO Late) Recruiting
Effects of Transcranial Magnetic Stimulation After Endovascular Treatment for Acute Ischemic Stroke Recruiting
Intravenous Thrombolytic Therapy for Acute Ischemic Stroke Patients with Low NIHSS and Non-disabling Deficits Starting soon
A Multicenter, Randomized Controlled Clinical Investigation to Evaluate the Safety and Effectiveness of the Super-Bore 8/7F Aspiration Catheters in the Treatment of Acute Intracranial Large Vessel Occlusion Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07045987 on ClinicalTrials.gov ↗ ← All trials in China