Antithrombotic Drug Use in Patients With Ischemic Stroke and Microbleeds

NCT05032053 · tracked via the Priya Life Science China tracker

Sponsor

Xijing Hospital

Phase

Observational

Started

2022-03-01

Last updated

2026-07-30

Condition(s) studied

Ischemic Stroke

Investigational drug(s) / intervention(s)

Antithrombotic drugs

Antithrombotic drugs: The purpose of our study is to observe the effect of various antithrombotic drugs on the prognosis of ischemic stroke patients with cerebral microbleeds.

Study summary

To observe the effect of different antithrombotic drugs on the prognosis of ischemic stroke patients with cerebral microbleeds. And further combined with proteomic methods to explore serological markers that can be used to accurately predict the prognosis of such patients.

Eligibility

Sex

ALL

Min age

40 Years

Max age

—

Healthy volunteers

Inclusion Criteria: 1. Patients diagnosed clinically as ischemic stroke; 2. Age ≥ 40 years; 3. Onset time ≤ 3 months; 4. Informed consent was signed. Exclusion Criteria: 1. Patients with symptomatic intracranial hemorrhage; 2. bleeding lesion \> 10 mm was found on SWI; 3. Vascular malformations, tumors, abscesses or other major non ischemic brain diseases were present; 4. There are contraindications for antithrombotic drugs use; 5. Serious systemic diseases; 6. Refusal to sign informed consent or poor compliance.

Primary outcome measure(s)

Increase of cerebral microbleeds — 1 year after onset
How many cerebral microbleeds increased after 1 year of antithrombotic drugs treatment. The number of microbleeds will be detected by MR-SWI.

Trial sites (16)

Facility	City	Region	Status
Ankang Central Hospital	Ankang	Shaanxi	Recruiting
3201 Hospital	Hanzhong	Shaanxi	Recruiting
Department of Neurology, Xijing Hospital, Fourth Military Medical University	Xi'an	Shaanxi	Recruiting
Yan'an University Affiliated Hospital	Ya'an	Shaanxi	Recruiting
Yulin No.2 Hospital	Yunlin	Shaanxi	Recruiting
Xi'AN GAOXIN Hospital	Xi'an	Shannxi	Recruiting
Hanzhong People's Hospital	Hanzhong	China	Recruiting
986 Hospital	Xi'an	China	Recruiting
Gaoling District Hospital	Xi'an	China	Recruiting
Gem Flower Xi'an Changqing Staff Hospital	Xi'an	China	Recruiting
Tangdu Hospital	Xi'an	China	Recruiting
The First Affiliated Hospital of Xi'an Medical University	Xi'an	China	Recruiting
No.215 Hospital of Shaanxi nuclear industry	Xianyang	China	Recruiting
The First People's Hospital of Xianyang	Xianyang	China	Recruiting
Xian Yang Central Hospital	Xianyang	China	Recruiting
Yan'an People's Hospital	Yan’an	China	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05032053 on ClinicalTrials.gov ↗ ← All trials in China