Sodium hyaluronate injection: The control group was injected into the joint cavity with sodium hyaluronate injection..
Study summary
To evaluate the safety and effectiveness of PRP injection therapy in the repair of osteoarthritis and periarticular soft tissue injury through a single-center, exploratory clinical study, and to provide a more reliable basis for the treatment of joint injury.
Eligibility
Sex
ALL
Min age
20 Years
Max age
60 Years
Healthy volunteers
No
Inclusion Criteria:
* The age range of the participants was 20 to 60 years old. Through a comprehensive clinical and imaging examination, it was conclusively determined that the individuals had knee osteoarthritis or experienced injuries to the cart, and meniscus surrounding the knee joint.
* The preoperative routine tests and examinations revealed no contraindications.
* Revised sentence: "Informed consent of the patient
Exclusion Criteria:
* The platelet count or function exhibits significant abnormalities、Systemic infection transmitted through the bloodstream.
* Prolonged usage of anti-inflammatory drugs and systemic corticoid administration.
* In injection site or damage to the skin.
* Patients with tumors or undergoing radiotherapy and chemotherapy.
* Pregnant or breastfeeding women.
* Individuals with mental illnesses who are unable to cooperate with follow-up procedures.
* Contraindications for MRI、Patients or their families do consent to participate in the study.
* Other circumstances that render participation in the study unsuitable.
Primary outcome measure(s)
X-ray — pre-operation,3 weeks after treatment, 6 months after treatment The postoperative plain X-ray film was utilized for the assessment of knee joint deformity, stenosis of the joint space, and hyperplasia of osteophytes.
CT — pre-operation,3 weeks after treatment, 6 months after treatment The application of three-dimensional CT scan for the assessment of articular cartilage defects.
MRI — pre-operation,3 weeks after treatment, 6 months after treatment The injury of ligaments, meniscus, and the knee joint was assessed using MRI.
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
We use cookies to analyse site traffic and improve your experience. With your consent, we may also use cookies for advertising. You can change your choice at any time on our Cookie Policy page. See also our Privacy Policy.