Repetitive Transcranial Magnetic Stimulation Therapy in Essential Tremor

NCT06145932 · tracked via the Priya Life Science China tracker

Sponsor

Second Affiliated Hospital of Soochow University

Phase

Not applicable

Started

2023-11-07

Last updated

2023-11-24

Condition(s) studied

Essential Tremor

Investigational drug(s) / intervention(s)

real rTMSsham rTMS

real rTMS: treated with 1HZ rTMS 1800 pulses / day,for 10 days

sham rTMS: treated with sham rTMS 1800 pulses / day,for 10 days

Study summary

The purpose of this study is to evaluate the efficacy and electrophysiology of repetitive transcranial magnetic stimulation in the treatment of essential tremor.

Eligibility

Sex

ALL

Min age

18 Years

Max age

80 Years

Healthy volunteers

Inclusion Criteria: 1. Diagnosed as essential tremor conforming to the diagnostic criteria for essential tremor in the tremor group of the International Parkinson's and Movement Disorders Society (IPMDS). 2. Signed informed consent form. Exclusion Criteria: 1. Complicated with brain organic diseases, epilepsy, other mental diseases, family history of dementia, metal devices implanted in the body and any contraindications to TMS; 2. History of craniocerebral surgery; 3. TMS cannot cooperate; 4. TMS-EEG examination artifacts are obvious, or cannot be analyzed due to other technical reasons.

Primary outcome measure(s)

The efficacy of the treatment on the essential tremor evaluated by Essential Tremor Rating Assessment Scale (TETRAS) score — visit 1(baseline), visit 2(Day 10), visit 3(Day 30)
The TETRAS is widely used tremor evaluation scale.TETRAS has been used for evaluation tremor in patients with essential tremor focuses primarily on the assessment of activities of daily living and tremor.The TETRAS score ranges from 0 to 112. The higher the TETRAS score, the more severe the symptoms.
Changes from baseline in tremor analysis — visit 1(baseline), visit 2(Day 10), visit 3(Day 30)
This outcome reflects quantitative changes in the patient's tremor.

Trial sites (1)

Facility	City	Region	Status
The Second Affiliated Hospital of Soochow University	Suzhou	China	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06145932 on ClinicalTrials.gov ↗ ← All trials in China