Temporal Interference: Researchers apply temporal interference (TI) stimulation to the deep brain nuclei of essential tremor patients.
Study summary
This single-center prospective study aims to investigate the treatment efficacy of temporal interference (TI) in essential tremor patients aged 30-70.
Eligibility
Sex
ALL
Min age
30 Years
Max age
70 Years
Healthy volunteers
No
Inclusion Criteria:
* Aged 30-70 years old, regardless of gender. Action tremor and postural tremor in both upper limbs, or action tremor and postural tremor in one limb;
* No history of mental diseases;
* Informed consent signed.
Exclusion Criteria:
* Presence of other neurological diseases affecting the study (such as epilepsy);
* Patients with moderate to severe cognitive impairment (Montreal Cognitive Assessment ≤ 18 points);
* Orthopedic diseases that may affect motor symptoms;
* Patients taking antipsychotic or antidepressant medications;
* Presence of metal implants in the body (such as brain pacemakers or cardiac pacemakers);
* History of electroconvulsive therapy;
* Presence of cardiovascular risk factors, etc.
Primary outcome measure(s)
Tremor Level Evaluation — Up to 3 months after TI stimulation Percentage change in per month after stimulation from baseline in The Essential Tremor Rating Assessment Scale(TETRAS) score. The TETRAS score ranges from 0 to 112, including an activities of daily living (ADL) section(0-48 scores) and a performance section(0-64 scores), with higher scores representing more severe tremor and lower scores indicating lower tremor level
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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