Detection of Microplastics and Nanoplastics in Neurosurgery Patients (DT-MiNi)

NCT05968053 · tracked via the Priya Life Science China tracker

Sponsor

Beijing Tiantan Hospital

Phase

Observational

Started

2023-09-25

Last updated

2025-01-23

Condition(s) studied

Carotid Artery StenosisGliomaIntracranial AneurysmIntracranial HemorrhagesBrain Tumor

Investigational drug(s) / intervention(s)

biological samples analysis

biological samples analysis: biological samples analysis

Study summary

Plastic particles are a ubiquitous pollutant in the living environment and food chain, so far, plenty of studies have reported the internal exposure of microplastics and nanoplastics in human tissues and enclosed body fluids.

Neurosurgery is the only department that can open the skull. In addition to blood and cerebrospinal fluid, there are brain tissue and tumors in the presence of lesions. Whether any of these microplastics and nanoplastics are present remains a mystery. This prospective observational study will harvest biological samples of neurosurgery patients.

The objective of this research is to be able to detect microplastics and nanoplastics on blood and operation samples of neurosurgery patients.

Eligibility

Sex

ALL

Min age

18 Years

Max age

80 Years

Healthy volunteers

Inclusion Criteria: * Age 18-80 years * Any type of neurosurgery Exclusion Criteria: ·refusal of the patient to participate

Primary outcome measure(s)

microplastics — baseline, intraoperative
Detection of microplastics in human brain tissue and the blood undergoing neurosurgery
nanoplastics — baseline, intraoperative
Detection of nanoplastics in human brain tissue and the blood undergoing neurosurgery

Trial sites (1)

Facility	City	Region	Status
Beijing Tiantan Hospital, Capital Medical University	Beijing	Beijing Municipality	Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05968053 on ClinicalTrials.gov ↗ ← All trials in China