Consistency of Carotid Doppler Blood Flow and Thermodilution Technique

Condition(s) studied

Investigational drug(s) / intervention(s)

passive leg raising: transfer a patient from semi-recumbent position to supine position with a 45° leg lifting

Dobutamine: infusion dobutamine

Study summary

Currently, the gold standard method to estimate CO is the thermodilution technique, pulmonary artery catheter (PAC) and PiCCO system included, however, the invasiveness and complexity of the thermodilution technique have limited their usefulness in many clinical scenarios. By measuring the carotid blood flow, continuous carotid doppler technique has been reported to noninvasively estimate cardiac output (CO) and other parameters related to cardiac contractility and fluid status in various cardiovascular disorders. However, to the best of our knowledge, few study has been reported to evaluate the consistency of this technique in cardiac surgery patients. The aim of this study is to evaluate the tracking ability of CO changes measured by continuous carotid doppler technique in cardiac surgery patients, use the thermodilution technique as the referenced.

Eligibility

Primary outcome measure(s)

• cardiac output by thermodilution method — 5 minutes after the patients was sedated
  measuring cardiac output using thermodilution method
• cardiac output by continuous carotid doppler blood flow — 5minutes after the patients was sedated
  measuring cardiac output using continuous carotid doppler blood flow
• cardiac output by thermodilution method — 2 minutes after passive leg raising
  measuring cardiac output using thermodilution method
• cardiac output by continuous carotid doppler blood flow — 2 minutes after passive leg raising
  measuring cardiac output using continuous carotid doppler blood flow
• cardiac output by thermodilution method — 15 minutes after termination of passive leg raising
  measuring cardiac output using thermodilution method
• cardiac output by continuous carotid doppler blood flow — 15 minutes after termination of passive leg raising
  measuring cardiac output using continuous carotid doppler blood flow
• cardiac output by thermodilution method — 30 minutes after dobutamine infusion
  measuring cardiac output using thermodilution method
• cardiac output by continuous carotid doppler blood flow — 30 minutes after dobutamine infusion
  measuring cardiac output using continuous carotid doppler blood flow

Trial sites (1)

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