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Clinical Trials in China / NCT05892042
Recruiting Not applicable

Anti-CoagulaTion on Left Ventricular Thrombus After ST Segment Elevation Myocardial Infarction

NCT05892042 · tracked via the Priya Life Science China tracker
Sponsor
Jilin University
Phase
Not applicable
Started
2023-05-01
Last updated
2026-06-01

Condition(s) studied

ST-segment Elevation Myocardial Infarction (STEMI)Left Ventricular Thrombus

Investigational drug(s) / intervention(s)

Rivaroxaban 15 MG [Xarelto] →

Rivaroxaban 15 MG [Xarelto]: Eligible subjects randomized into experimental group will receive rivaroxaban 15mg daily in addition to dual anti platelet therapy unless confirmed resolution of the left ventricular thrombus.

Study summary

Contemporary data are lacking regarding the management of left ventricular thrombus (LVT) developed after ST segment elevation myocardial infarction

Eligibility

Sex
ALL
Min age
18 Years
Max age
80 Years
Healthy volunteers
No
Inclusion Criteria: Established ST segment elevation myocardial infarction within 7 days Left ventricular thrombus (LVT) is detected by either cardiac magnetic resonance (CMR) or TTE. Ongoing treatment with dual anti-platelet therapy according to ESC/AHA guidelines at the time of randomization Exclusion Criteria: Clinically or hemodynamically unstable planed major surgeon such as CABG or Valve replacement within next 12 months Concomitant condition that requires anti- coagulation therapy, such as AF, DVT. Any contraindication of anticoagulant therapy History of intracranial hemorrhage; Woman who is currently pregnant, or breastfeeding serious impaired renal and liver functions life expectancy less than 1 year can not provide consent

Primary outcome measure(s)

  • Percentage of participants with the first occurrence of Stroke and other systemic embolism — 12 months
    The percentage of participants with the first occurrence of Stroke and other systemic embolism were evaluated.

Trial sites (1)

FacilityCityRegionStatus
Jilin university Changchun Jilin Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05892042 on ClinicalTrials.gov ↗ ← All trials in China