Optimization Strategy of Carotid Artery Stenosis

Condition(s) studied

Investigational drug(s) / intervention(s)

Carotid revascularization: All patients received carotid revascularization surgery at Peking Union Medical College Hospital.

MRI-PWI: Multi-modal MRI before and after surgery.

CTA: CTA before and after surgery.

PET/MRI: PET/MRI before surgery.

Ultrasound: Ultrasound before and after surgery.

Study summary

The goal of this observational study is to learn about how to utilize multiple evaluation techniques in carotid artery stenosis patients for optimizing assessment of diagnosis and treatment strategy.

The main questions it aims to answer are:

* Identify best strategy that use multi-modal MRI and CT to assess patients' cerebral lesions and perfusion.
* Identify best strategy that use multi-modal MRI, PET-MRI ultrasound and CT to assess components and characters of patients' carotid plaques.

Participants will accept imaging examination before and after surgery. And doctors will collect basic characteristics, imaging results and biological samples of patients for analysis.

Eligibility

Primary outcome measure(s)

• stroke — During hospital stay, usually 7-30 days post operation
  perioperative stroke
• cardiac infarction — During hospital stay, usually 7-30 days post operation
  perioperative cardiac infarction
• transient ischemic attack — During hospital stay, usually 7-30 days post operation
  perioperative transient ischemic attack
• cerebral hyperperfusion syndrome — During hospital stay, usually 7-30 days post operation
  perioperative cerebral hyperperfusion syndrome
• death — During hospital stay, usually 7-30 days post operation
  perioperative death

Trial sites (1)

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