POPRC+OIN: Pelvic-organ preserving radical cystectomy with orthotopic ileal neobladder
SRC+OIN: Standard radical cystectomy with orthotopic ileal neobladder
Study summary
To compare the urinary continence rate and long-term oncological outcomes of pelvic-organ preserving radical cystectomy (POPRC) with orthotopic ileal neobladder (OIN) versus standard radical cystectomy(SRC) with OIN.
Eligibility
Sex
FEMALE
Min age
55 Years
Max age
75 Years
Healthy volunteers
No
Inclusion Criteria:
1. Female patients aged between 55-75.
2. Patients those who are diagnosed with organ-confined urothelial carcinoma(\<pT3)
3. Patients those who are capable for radical cystectomy with orthotopic ileal neobladder.
4. ECOG score between 0-2;
5. Normal renal function;
6. Patients those who volunteer to participate in this study and sign the informed consents.
7. Patients those who are able to cooperate in the study.
Exclusion Criteria:
1. Absence of tumour in bladder neck or urethra;
2. Patients thsoe who are diagnosed distant metastasis before surgery.
3. Previous history of malignancy of pelvic organs or surgical resection of pelvic organs;
4. Patients those who are diagnosed with other malignancies.;
5. Patients those who had received pelvic radiotherapy or major pelvic operation.
6. Pregnancy status;
7. Any other conditions that the researcher considers to be excluded from this study
Primary outcome measure(s)
day-time and night-time continence rate — 6 months We will use pad-test to evaluate the urinary continence for patients
Trial sites (1)
Facility
City
Region
Status
Sun Yat-Sen Memorial Hospital
Guangzhou
Guangdong
More Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University trials in China
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
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