Hyperbaric Oxygen in the Prevention of Radiation Pneumonitis
Condition(s) studied
Investigational drug(s) / intervention(s)
hyperbaric oxygen therapy: hyperbaric oxygen therapy
Study summary
Radiotherapy is one of the important treatments to improve the survival rate of breast cancer patients, but also has the risk of radiation lung injury, which can develop into pulmonary fibrosis. Hyperbaric oxygen can improve the tissue after radiation by promoting the function of vascular endothelial cells and fibroblasts, and reducing the secretion of inflammatory factors, thereby inhibiting the process of fibrosis and fiber atrophy after radiotherapy, and promoting tissue repair. Therefore, it has the potential value of treating chronic radiation injury. We aim to investigate whether hyperbaric oxygen treatment can reduce the incidence of radiation pneumonia and improve patients' quality of life, and to evaluate its safety and the impact on the patients' long-term survival outcomes.
Eligibility
Primary outcome measure(s)
- Incidence of radiation pneumonitis — 1 year
Rate of enrolled participants with radiation pneumonitis
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| Guangdong Provincial People's Hospital | Guangzhou | Guangdong | Recruiting |
More Guangdong Provincial People's Hospital trials in China
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT05189496 on ClinicalTrials.gov ↗ ← All trials in China