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Clinical Trials in China / NCT05112211
Recruiting Not applicable

Multi-model Image of Doxycycline in TAO

NCT05112211 · tracked via the Priya Life Science China tracker
Sponsor
Sun Yat-sen University
Phase
Not applicable
Started
2022-01-01
Last updated
2023-11-22

Condition(s) studied

Thyroid Associated Ophthalmopathy

Investigational drug(s) / intervention(s)

Doxycycline Hyclate →

Doxycycline Hyclate: patients administrated with doxycycline tablets 100mg orally per day

Study summary

This study aims to evaluate the efficacy of doxycycline treating Thyroid Associated Ophthalmopathy by multi-modal image.

Eligibility

Sex
ALL
Min age
18 Years
Max age
70 Years
Healthy volunteers
No
Inclusion Criteria: * Informed consent * Age 18-70 years old * Diagnosed with TAO Exclusion Criteria: * Sight-threatening TAO with dysthyroid optic neuropathy * Allergy of tetracycline * Have contraindications of MRI(metal pacemaker, fake teeth, foreign body and other materials which will disturb the examination)

Primary outcome measure(s)

  • change of extraocular muscle volume and orbital fat volume by MRI — at month 6
    3D MRI image will be established and the volume of extraocular muscle and orbital fat will be calculated by the same advanced programmer who is blinded of the pre- or post- treatment images order. A higher score means a better outcome.

Trial sites (1)

FacilityCityRegionStatus
Zhongshan Ophthalmic Center Guangzhou Guangdong Recruiting

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Other trials for the same condition

Establishment of Multiparametric Prediction Models for Moderate to SevereThyroid Associated Ophthalmopathy Recruiting
Construction and Application of Precise Diagnosis and Treatment System for Thyroid-associated Ophthalmopathy Recruiting
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT05112211 on ClinicalTrials.gov ↗ ← All trials in China