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Trackers› Clinical trials› Canada
Clinical trial register · Canada

Studies with a Canadian investigative site

Every study on the ClinicalTrials.gov registry that lists a site in Canada and is open, about to open, active-but-closed, or enrolling by invitation. Filter it, cite it, and take it away as a file.

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Source: ClinicalTrials.gov, U.S. National Library of Medicine. Complete coverage โ€” all 6540 matching records held by the registry are in this view. Synced 26 Sep 2026, 19:55 UTC
6540
Studies in scope
all four open statuses
3515
Recruiting now
open to new participants
887
Lead sponsors
across recruiting studies
Top sites
Toronto 2809 Montreal 1902 Vancouver 1179 Calgary 1061 Edmonton 1017
Narrow the register
Recruitment status
Phase
Lead sponsor
University Health Network, Toronto349 University of British Columbia197 AstraZeneca190 University of Alberta180 University of Calgary149
Site location
Toronto2809 Montreal1902 Vancouver1179 Calgary1061 Edmonton1017
All 255 locations
Target enrolment
to

Trials in this register

6540 of 6540 studies
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Status
Study
Lead sponsor
Phase
Enrol
Sites in Canada
Start
Not yet open
Effectiveness of a PMT Intervention to Reduce Alcohol in Young Adults
NCT06615648Behavior, Drinking, Alcohol Drinking, Colorectal Cancer Control and Prevention, Healthy Volunteers
Western University, Canada
Not applicable
152
London
2024-11-01
By invitation
Virtual Kidney Check and Follow-up
NCT06223750Kidney Disease, Chronic
University of Manitoba
Not applicable
3,356
Winnipeg
2024-11-01
By invitation
Long-term Follow up of the Stability 1 Trial
NCT06885372LET, ACL Reconstruction, Osteoarthritis (OA) of the Knee
Western University, Canada
Not applicable
510
Banff, Calgary, New Westminster, Winnipeg, Hamilton, Kingston, London
2024-11-01
Recruiting
Deep Brain Stimulation for Refractory PTSD
NCT06705296PTSD
Sunnybrook Health Sciences Centre
Phase 1
20
Toronto
2024-11-01
Active, closed
Psilocybin for Treatment-Resistant Depression in Autism
NCT06731621Treatment Resistant Depression, Autism Spectrum Disorder
DrugPsilocybin
Centre for Addiction and Mental Health
Phase 1
20
Toronto
2024-11-01
Active, closed
REduced-dose Steroid PrOtocol for Childhood Nephrotic SyndromE (RESPONSE)
NCT06635720Nephrotic Syndrome in Children, Nephrotic Syndrome, Minimal Change, Nephrotic Syndrome, Nephrotic Syndrome๏ผŒIdiopathic
DrugsPrednisolone·Prednisone
The Hospital for Sick Children
Phase 3
50
Toronto
2024-11-01
Not yet open
Effectiveness of Zirconia Glaze Removal and Polish in the Treatment of Peri-implant Mucositis
NCT06619158Peri-Implantitis and Peri-implant Mucositis
University of Manitoba
Not applicable
44
Winnipeg
2024-11-01
Recruiting
DBS for Cognitive Deficits After Traumatic Brain Injury
NCT06818864TBI Traumatic Brain Injury
Sunnybrook Health Sciences Centre
Phase 1
10
Toronto
2024-11-01
Not yet open
The ATP Project (Antipsychotic-TEP-Psychosis)
NCT06651112First Episose Psychosis, Metabolic Disease, Psychosis; Episode
Universitรฉ de Sherbrooke
Observational
18
Sherbrooke
2024-11-01
Not yet open
Postexercise Hot-Water Immersion on Exercise Performance in Hypoxia
NCT06672614Heat Exposure, Exercise Training
Nipissing University
Not applicable
20
North Bay
2024-11-01
Recruiting
A Study of Toripalimab in Combination With Cisplatin and Gemcitabine in Participants With Recurrent Metastatic Nasopharyngeal Cancer
NCT06457503Nasopharyngeal Cancer Recurrent
DrugsToripalimab·Gemcitabine·Cisplatin·Carboplatin
Coherus Oncology, Inc.
Phase 4
100
Toronto
2024-11-01
Recruiting
Improving Sleep to Prevent Depression & Anxiety in Adolescents at High Risk
NCT06358495Insomnia, Sleep Disturbance, Depressive Symptoms, Anxiety Symptoms
University of Calgary
Not applicable
50
Calgary
2024-11-01
Recruiting
Assessing the Impact of DAy Programs on Individuals Living with Dementia and Their Family/friend Caregivers
NCT06496945Adult Day Programs, Continuing Care, Old Age; Dementia, Family/Friend Caregivers
York University
Observational
3,000
Edmonton & Calgary, Multiple, Winnipeg
2024-11-01
Not yet open
Powdered Intrawound Vancomycin in Open Fractures Trial
NCT06504992Open Fracture, Trauma, Infection, Surgical Site, Fractures, Open
DrugVancomycin
University of Manitoba
Phase 4
350
Winnipeg
2024-11-01
Recruiting
Effect of peRiopErative duLoxetIne Administration on Opioid Consumption Following Total kneE Arthroplasty (RELIFE)
NCT06423716Knee Osteoarthritis
DrugDuloxetine
Sunnybrook Health Sciences Centre
Phase 4
150
Toronto
2024-11-01
Recruiting
Domain-specific Aerobic Exercise Training in Coronary Artery Disease
NCT06143332Coronary Artery Disease
Western University, Canada
Not applicable
105
London
2024-11-01
Recruiting
PENG Block vs. Intraoperative Local Anesthetic Infiltration for Total Hip Arthroplasty
NCT05898581Anesthesia
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Not applicable
60
London
2024-11-01
Not yet open
The Impact of a Dexmedetomidine Perfusion on Intraoperative Remifentanil Consumption
NCT06684197Dexmedetomidine, Total Intravenous Anesthesia, Remifentanil Consumption, Remifentanil
DrugDexmedetomidine
Ciusss de L'Est de l'รŽle de Montrรฉal
Not applicable
72
Montreal
2024-11
Recruiting
Rapid MRI for Assessing Functional Abilities and Predicting TBI Outcomes
NCT06454591Traumatic Brain Injury
D.J Cook
Observational
300
Calgary, Kingston
2024-11
Not yet open
The Effects of Metformin on Morbidity and Mortality in Elderly Patients
NCT04530058Burns
DrugMetformin
Hamilton Health Sciences Corporation
Phase 2
250
Hamilton
2024-11
Recruiting
Sotagliflozin to Slow Kidney Function Decline in Persons With Type 1 Diabetes and Diabetic Kidney Disease
NCT06217302Diabetic Nephropathies, Kidney Failure, Chronic, Diabetes Mellitus Type 1, Heart Failure
DrugSotagliflozin
Alessandro Doria
Phase 3
150
Calgary, Edmonton, Vancouver, Toronto, Montreal
2024-10-31
Recruiting
Silmitasertib (CX-4945) in Combination With Chemotherapy for Relapsed Refractory Solid Tumors
NCT06541262Neuroblastoma, Ewing Sarcoma, Osteosarcoma, Rhabdomyosarcoma
DrugsVincristine·Temozolomide·Irinotecan
Milton S. Hershey Medical Center
Phase 1/2
104
Montreal
2024-10-30
Recruiting
Phase 1b Study of VERVE-201 in Patients With Refractory Hyperlipidemia
NCT06451770Hypercholesterolemia, Hypertriglyceridemia, Refractory Hyperlipidemia
Verve Therapeutics, Inc.
Phase 1
36
Chicoutimi, Montreal, Toronto
2024-10-30
Recruiting
Changes in Velocimetric Indices of Uterine and Umbilical Arteries Before and After Combined Spinal-epidural Analgesia in Laboring Women (PART II)
NCT06655675Labor Pain
Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Not applicable
54
Toronto
2024-10-30
Recruiting
A Study to Investigate the Safety and Efficacy of SAR446523 Injected Subcutaneously in Adult Participants With Relapsed/Refractory Myeloma
NCT06630806Plasma Cell Myeloma Refractory
Sanofi
Phase 1
87
Vancouver, Montreal, Sherbrooke
2024-10-30
Active, closed
SpaceIT Hydrogel System for Perirectal Spacing
NCT06451614Prostate Cancer
Boston Scientific Corporation
Not applicable
230
Ottawa, Toronto
2024-10-30
Recruiting
Impacts of the VEGA Family Violence Education Resources for Psychology Trainees
NCT06630598Family Violence
University of Ottawa
Not applicable
90
Ottawa
2024-10-30
Recruiting
A Study Investigating Subcutaneously Administered Pozelimab in Combination With Cemdisiran or Cemdisiran Alone in Adult Participants With Geographic Atrophy
NCT06541704Age-related Macular Degeneration (AMD), Geographic Atrophy (GA)
DrugsCemdisiran·Pozelimab
Regeneron Pharmaceuticals
Phase 3
975
Ottawa, Quรฉbec
2024-10-30
Recruiting
Post-Extubation Assessment of Clinical Stability in ELBW Infants
NCT06037083Extremely Low Birth Weight Infants
McGill University Health Centre/Research Institute of the McGill University Health Centre
Observational
20
Montreal
2024-10-29
Active, closed
A Study of Mosliciguat in PH-ILD
NCT06635850Pulmonary Hypertension, Interstitial Lung Disease, Lung Diseases, Vascular Diseases
DrugMosliciguat
Pulmovant, Inc.
Phase 2
135
Calgary, London, Toronto
2024-10-29
Recruiting
Lemborexant Treatment of Insomnia Linked to Epilepsy
NCT06262594Epilepsy, Sleep
DrugLemborexant
University of Manitoba
Phase 3
26
Winnipeg
2024-10-29
Active, closed
Narrative Enhancement and Cognitive Therapy for Self-Stigma in Youth
NCT06672562Bipolar Disorder, Multiple Mental Health Conditions
Centre for Addiction and Mental Health
Not applicable
96
Toronto
2024-10-28
Active, closed
IMPACT 360 for Parkinson's Disease
NCT07443293Parkinson's Disease (PD), REM Sleep Behavior Disorder
University of British Columbia
Phase 2
60
Vancouver
2024-10-28
Recruiting
Relative Bioavailability of Two Orally Administered CBD Formulations in Healthy Male Adults
NCT06574100Pharmacokinetics
DrugCannabidiol
University of Saskatchewan
Phase 1
20
Saskatoon
2024-10-26
Recruiting
Nutritional Supplementation in Head and Neck Cancers
NCT05379712Malnourishment, Nutritional Deficiency, Undernutrition
AHS Cancer Control Alberta
Phase 2
81
Edmonton
2024-10-25
By invitation
Social Media for Colorectal Cancer Screening
NCT04296630Colorectal Cancer, Cancer Screening
Unity Health Toronto
Not applicable
56,000
Toronto
2024-10-25
Recruiting
I-CARE: A Pilot Study of Cognitive Behavioural Therapy(CBT) for Mood and Anxiety Disorders
NCT06532500Mood Disorders, Anxiety Disorders
Sunnybrook Health Sciences Centre
Not applicable
50
Toronto
2024-10-24
Active, closed
A Study of Remternetug (LY3372993) in Early Alzheimer's Disease (TRAILRUNNER-ALZ 3)
NCT06653153Alzheimer's Disease
DrugRemternetug
Eli Lilly and Company
Phase 3
1,400
Chicoutimi, Greenfield Park, Kelowna, Lรฉvis, Montreal, Ottawa, Peterborough, Quรฉbec
2024-10-24
Recruiting
Perfectionism and Daily Coping and Emotion Regulation Processes: A Trial of Two Explanatory Feedback Interventions
NCT06625151Perfectionism, Psychological Well-being, University Students
McGill University
Not applicable
200
Montreal
2024-10-23
Recruiting
A Study to Learn How PF-06821497 (Mevrometostat) Works in Men With Metastatic Castration-resistant Prostate Cancer.
NCT06629779Metastatic Castration-Resistant Prostate Cancer
DrugsMevrometostat·Xtandi·Enzalutamide
Pfizer
Phase 3
900
Calgary, Edmonton, Halifax, Oshawa, Chicoutimi, Montreal
2024-10-22
Active, closed
Study to Evaluate Avacopan in Combination With a Rituximab or Cyclophosphamide-containing Regimen, in Children From 6 Years to < 18 Years of Age With AAV.
NCT06321601Vasculitis
DrugAvacopan
Amgen
Phase 3
19
Calgary, Edmonton, Vancouver, Montreal
2024-10-22
Recruiting
A Study of Lower Radiotherapy Dose to Treat Children With CNS Germinoma
NCT06368817Basal Ganglia Germinoma, Diabetes Insipidus, Germinoma, Pineal Region Germinoma
DrugsEtoposide·Carboplatin
Children's Oncology Group
Phase 2
240
Edmonton, Vancouver, Winnipeg, Halifax, Hamilton, London, Toronto, Montreal
2024-10-22
Recruiting
Patient Reported Outcomes Targeting Early Chest Tube Removal (PROTECTR) Study
NCT06444854Lung Surgery, Chest Tube Removal, Enhanced Recovery After Surgery (ERAS)
London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Not applicable
130
London
2024-10-22
Recruiting
Patient Reported Experiences and Outcomes Associated with Standard C-Section Wound Closure Versus STRATAFIX/DERMABOND PRINEO Wound Closure (CS-PREO)
NCT06614829Cesarean Section; Complications, Wound, Infection (Following Delivery)
North York General Hospital
Not applicable
68
North York
2024-10-22
Recruiting
Adjunctive Treatment With L-methylfolate for Treatment-Resistant Generalized Anxiety Disorder: a Pilot Study
NCT06218030Generalized Anxiety Disorder
Queen's University
Phase 4
10
Kingston
2024-10-22
Recruiting
Alternative Physical Activity Strategies for Breast Cancer Survivors
NCT06633380Breast Cancer, Insulin Resistance, Cardiometabolic Risk Factors
University of Toronto
Not applicable
24
Toronto
2024-10-22
Active, closed
A Study to Learn About the Investigational Medicine Called PF-06821497 (Mevrometostat) in Men With mCRPC Who Were Previously Treated With Abiraterone Acetate for Prostate Cancer (MEVPRO-1).
NCT06551324Metastatic Castrate Resistant Prostate Cancer (mCRPC)
DrugsMevrometostat·Xtandi·Taxotere·Enzalutamide
Pfizer
Phase 3
600
Calgary, Vancouver, Toronto, Montreal
2024-10-21
Recruiting
A Study of Pembrolizumab (MK-3475) With or Without Intismeran Autogene (V940) in Participants With Non-small Cell Lung Cancer (V940-009/INTerpath-009)
NCT06623422Carcinoma, Non-Small-Cell Lung
DrugsIntismeran autogene·Pemetrexed·Gemcitabine·Paclitaxel
Merck Sharp & Dohme LLC
Phase 3
680
Halifax, Hamilton, Kingston, Oshawa, Toronto, Montreal, Quรฉbec
2024-10-21
Recruiting
Pericardiotomy in Cardiac Surgery
NCT06486636Atrial Fibrillation, Atrial Flutter, Cardiac Events
Population Health Research Institute
Not applicable
1,400
Hamilton
2024-10-21
Active, closed
Radiographic Migration Analysis of the ATTUNE Cementless CR Fixed-Bearing Total Knee Replacement
NCT06189872Osteo Arthritis Knee
Canadian Radiostereometric Analysis Network
Not applicable
30
Winnipeg, Halifax, London
2024-10-21
Recruiting
A Pilot Crossover Trial of Prophylactic Wilate Compared to Placebo for Heavy Menstrual Bleeding in Patients with VWD
NCT06205095Von Willebrand Diseases
Unity Health Toronto
Phase 3
20
Toronto
2024-10-21
Recruiting
Transcranial Direct Current Stimulation and Yoga for Knee Osteoarthritis
NCT06228573Knee Osteoarthritis
McMaster University
Not applicable
68
Hamilton, London, Sherbrooke
2024-10-20
Recruiting
A Study of Amivantamab and mFOLFOX6 or FOLFIRI Versus Cetuximab and mFOLFOX6 or FOLFIRI as First-line Treatment in Participants With KRAS/NRAS and BRAF Wild-type Unresectable or Metastatic Left-sided Colorectal Cancer
NCT06662786Colorectal Neoplasms
DrugsLeucovorin calcium/Levoleucovorin·Erbitux·Amivantamab·Adrucil
Janssen Research & Development, LLC
Phase 3
1,000
Calgary, Ottawa, Toronto, Montreal
2024-10-18
Recruiting
Evaluation of Efficacy and Safety of VX-993 for Pain Associated With Diabetic Peripheral Neuropathy
NCT06619860Diabetic Peripheral Neuropathic Pain
DrugPregabalin
Vertex Pharmaceuticals Incorporated
Phase 2
300
Brampton, Kelowna, Montreal, Toronto
2024-10-18
Recruiting
J-Valve Transfemoral Pivotal Study
NCT06455787Aortic Valve Regurgitation, Aortic Valve Disease Mixed
JC Medical, Inc., an affiliate of Edwards Lifesciences LLC
Not applicable
194
Vancouver, Toronto
2024-10-17
Active, closed
A Clinical Trial to Learn About the Effects of VHB937 in People With Amyotrophic Lateral Sclerosis (ALS)
NCT06643481Amyotrophic Lateral Sclerosis (ALS)
DrugVHB937
Novartis Pharmaceuticals
Phase 2
251
Calgary, Montreal
2024-10-17
Recruiting
Evaluation and Treatment of Adhesive Capsulitis Using Non-invasive Neurostimulation Devices
NCT06795932Adhesive Capsulitis of the Shoulder, Frozen Shoulder
Universitรฉ du Quรฉbec ร  Chicoutimi
Not applicable
30
Saguenay
2024-10-17
By invitation
A Study of the Safety and Efficacy of Prime Editing (PM359) in Participants With p47phox Autosomal Recessive Chronic Granulomatous Disease (CGD )
NCT06559176Chronic Granulomatous Disease, Granulomatous Disease, Chronic
Prime Medicine, Inc.
Phase 1/2
12
Montreal
2024-10-17
Active, closed
A Phase 1, Randomized, Double-blind, Placebo-controlled Study Evaluating AMG 691 in Healthy Participants and Participants With Mild-to-Moderate Asthma
NCT06637371Asthma
DrugAMG 691
Amgen
Phase 1
21
Winchester
2024-10-16
Recruiting
Playing Piano to Improve Hand Function Early After Stroke
NCT06621771Stroke
McGill University
Not applicable
30
Laval
2024-10-15
Recruiting
DETECTion of PeriOperative Atrial Fibrillation After Noncardiac Surgery
NCT06519747Atrial Fibrillation, Atrial Flutter
Population Health Research Institute
Observational
750
Hamilton, London, St. Catharines, Sherbrooke
2024-10-15
Recruiting
Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis and Anti-TNFฮฑ Inadequate Response
NCT06641089Arthritis, Psoriatic
DrugsSonelokimab·Risankizumab
MoonLake Immunotherapeutics AG
Phase 3
600
Toronto, Calgary, Trois-Riviรจres, Waterloo, Winnipeg
2024-10-15
Recruiting
Deep Brain Stimulation for Refractory Trigeminal Neuralgia with a Pontine Lesion
NCT05451251Trigeminal Neuralgia
Universitรฉ de Sherbrooke
Phase 1
6
Sherbrooke
2024-10-15
Recruiting
Pilot Study of the 'Thriving With PMDs' Program
NCT06648382Premenstrual Disorder, Premenstrual Dysphoric Disorder
University of Regina
Not applicable
50
Regina
2024-10-15
Active, closed
Evaluation of Sonelokimab in Patients With Active Psoriatic Arthritis Naive to Biologic Disease-Modifying Antirheumatic Drug
NCT06641076Arthritis, Psoriatic
DrugSonelokimab
MoonLake Immunotherapeutics AG
Phase 3
960
Calgary, Trois-Riviรจres, Waterloo, Winnipeg
2024-10-15
Recruiting
Maitake for Integrative Cancer Care
NCT06323473Cancer
The Canadian College of Naturopathic Medicine
Phase 2
40
Ottawa, Toronto
2024-10-15
Active, closed
A Phase III, Randomised Study of Adjuvant Dato-DXd in Combination With Rilvegostomig or Rilvegostomig Monotherapy Versus Standard of Care, Following Complete Tumour Resection, in Participants With Stage I Adenocarcinoma NSCLC Who Are ctDNA-positive or Have High-risk Pathological Features
NCT06564844Non-small Cell Lung Cancer
DrugsRilvegostomig·Vinorelbine·Datopotamab Deruxtecan·Etoposide
AstraZeneca
Phase 3
25
Halifax, Oshawa, Montreal
2024-10-15
Recruiting
Study of ATX-01 in Participants With DM1
NCT06300307Myotonic Dystrophy 1
ARTHEx Biotech S.L.
Phase 1/2
56
Chicoutimi
2024-10-15
Recruiting
Phase I Study of [177Lu]Lu-NNS309 in Patients With Pancreatic, Lung, Breast and Colorectal Cancers
NCT06562192Pancreatic Ductal Adenocarcinoma, Non-small Cell Lung Cancer, HR+/HER2- Ductal and Lobular Breast Cancer, Triple Negative Breast Cancer
Novartis Pharmaceuticals
Phase 1
162
Toronto, Montreal
2024-10-15
Recruiting
Early Atrial Fibrillation Ablation for Stroke Prevention in Patients With High Comorbidity Burden (EASThigh-AFNET 11)
NCT06324188Atrial Fibrillation
Atrial Fibrillation Network
Not applicable
2,312
Multiple Locations
2024-10-14
Recruiting
A Study to Evaluate ALN-HTT02 in Adult Patients With Huntington's Disease
NCT06585449Huntington's Disease
Alnylam Pharmaceuticals
Phase 1
66
Edmonton, Montreal, Ottawa, Vancouver
2024-10-14
Active, closed
Evaluation of Maralixibat in Pruritus Associated With General Cholestatic Liver Disease (EXPAND)
NCT06553768Cholestatic Liver Disease (Except ALGS, PFIC, PBC and PSC)
DrugMaralixibat
Mirum Pharmaceuticals, Inc.
Phase 3
90
Edmonton
2024-10-14
Recruiting
Cessation of Somatostatin Analogues After PRRT in Mid, Hind-Gut and Pancreatic Neuroendocrine Tumours
NCT06345079Neuroendocrine Tumors
Australasian Gastro-Intestinal Trials Group
Phase 2
78
Edmonton, Vancouver, London, Ottawa, Toronto, Regina, Saskatoon
2024-10-14
Recruiting
LIVERAGEโ„ข: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Moderate or Advanced Liver Fibrosis
NCT06632444Metabolic Dysfunction Associated Steatohepatitis (MASH), Liver Fibrosis
Boehringer Ingelheim
Phase 3
1,800
Calgary, Vancouver, Bridgewater, Toronto, Montreal, Terrebonne, Quรฉbec
2024-10-14
Recruiting
A Study Observing Everyday Effectiveness and Safety of the Drug Elafibranor in Participants With Primary Biliary Cholangitis Who Are Receiving Ongoing Treatment
NCT06447168Primary Biliary Cholangitis
Ipsen
Observational
424
Montreal, Calgary, London, Ottawa, Vancouver
2024-10-14
Recruiting
Beamion PANTUMOR-1: A Study to Test Whether Zongertinib Helps People With Advanced Cancers With HER2 Alterations
NCT06581432Solid Tumours
DrugZongertinib
Boehringer Ingelheim
Phase 2
588
Edmonton, Vancouver, Toronto, Montreal
2024-10-11
Active, closed
A Study to Evaluate the Safety and Efficacy of Axatilimab in Combination With Ruxolitinib in Participants With Newly Diagnosed Chronic Graft-Versus-Host Disease
NCT06388564Chronic Graft-versus-host-disease
DrugsAxatilimab·Prednisolone·Methylprednisolone·Ruxolitinib
Incyte Corporation
Phase 2
130
Calgary, Toronto, Montreal, Vancouver
2024-10-11
Recruiting
Third Enhanced Control of Hypertension and Thrombectomy Stroke Domain Within ACT-GLOBAL Adaptive Platform Trial
NCT06352619Ischemic Stroke, Acute
The George Institute
Not applicable
2,000
Calgary
2024-10-11
Recruiting
Cannabis for Chronic Headaches in Adolescents: the CAN-CHA Trial
NCT05337033Chronic Migraine
DrugMPL-001
University of Manitoba
Phase 2
20
Vancouver, Halifax, Toronto
2024-10-11
Active, closed
A Study of BMS-986484 Alone and Combination Therapy in Participants With Advanced Solid Tumors
NCT06544655Advanced Solid Tumors
DrugsCalcium folinate·Fluorouracil·Nivolumab·Capecitabine
Bristol-Myers Squibb
Phase 1
213
Toronto, Montreal
2024-10-10
Recruiting
Study of XmAb942 in Healthy Participants and Participants With Ulcerative Colitis
NCT06619990Ulcerative Colitis (UC)
Xencor, Inc.
Phase 1/2
270
London, Montreal, Scarborough, Vancouver
2024-10-10
Recruiting
Prednisone for CRPS in Distal Radius Fracture
NCT06453447Complex Regional Pain Syndromes, Distal Radius Fractures
DrugPrednisone
University of British Columbia
Not applicable
40
Vancouver
2024-10-10
Recruiting
Detection of Endometrial Cancer Through Risk Modelling
NCT06268626Endometrial Cancer
University of British Columbia
Observational
1,000
Vancouver
2024-10-10
Active, closed
CARE-ID: Dynamics of Respiratory Infections in Children and Transmission in Households and Schools
NCT06640387SARS CoV 2 Infection, RSV Infection, Influenza, Mycoplasma Pneumoniae
The Hospital for Sick Children
Observational
500
Toronto
2024-10-10
Recruiting
A Study of Eltrekibart and Mirikizumab in Adult Patients With Moderately to Severely Active Ulcerative Colitis
NCT06598943Ulcerative Colitis, Ulcerative Colitis Chronic
DrugsEltrekibart·Mirikizumab
Eli Lilly and Company
Phase 2
143
London, Montreal
2024-10-10
Active, closed
A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN1)
NCT06516952Prurigo Nodularis
DrugPovorcitinib
Incyte Corporation
Phase 3
349
Calgary, Edmonton, Sherwood Park, Barrie, Cobourg, London, Toronto, Quรฉbec
2024-10-10
Active, closed
A Study to Evaluate the Efficacy and Safety Study of Povorcitinib in Participants With Prurigo Nodularis (STOP-PN2)
NCT06516965Prurigo Nodularis
DrugPovorcitinib
Incyte Corporation
Phase 3
346
Edmonton, Barrie, London, Toronto, Quรฉbec, Saskatoon
2024-10-10
Active, closed
A Study to Evaluate IPN10200 Safety and Efficacy in the Prevention of Episodic or Chronic Migraine in Adults
NCT06625060Episodic Migraine, Chronic Migraine
DrugCorabotase
Ipsen
Phase 2
670
Calgary, Lรฉvis, Quรฉbec, Red Deer, Sarnia
2024-10-10
Recruiting
A First-in-human Study of KK8123 in Adults With X-linked Hypophosphatemia
NCT06525636X-linked Hypophosphatemia
Kyowa Kirin Co., Ltd.
Phase 1/2
39
Oakville
2024-10-09
Active, closed
Study of Emactuzumab for Tenosynovial Giant Cell Tumor (TGCT)
NCT05417789TGCT
DrugEmactuzumab
SynOx Therapeutics Limited
Phase 3
128
Calgary, Toronto, Montreal
2024-10-09
Active, closed
Study to Compare an Oral Weekly Islatravir/Lenacapavir Regimen With Bictegravir/Emtricitabine/Tenofovir Alafenamide in Virologically Suppressed People With HIV-1
NCT06630286HIV-1-infection
DrugsISL/LEN·B/F/TAF
Gilead Sciences
Phase 3
609
Montreal, Vancouver
2024-10-09
Active, closed
Neurobiological Effects of Psilocybin in Treatment Resistant Bipolar Depression
NCT06506019Bipolar Depression
DrugPsilocybin
University Health Network, Toronto
Phase 1
30
Toronto
2024-10-09
Recruiting
Longitudinal Study to Investigate Different Transcranial Electrical Stimulation
NCT06877312Dementia; Degenerative, Dementia Mixed
University of Manitoba
Not applicable
200
Winnipeg
2024-10-09
Recruiting
Open Lung Protective Extubation Following General Anesthesia
NCT06296173Intra-abdominal Surgery, Anesthesia, Lung Injury, Ventilator-Induced Lung Injury
Centre hospitalier de l'Universitรฉ de Montrรฉal (CHUM)
Not applicable
270
Vancouver, Ottawa, Toronto, Montreal, Quรฉbec
2024-10-08
Recruiting
Support-t Online Training in Youth Living With Type 1 Diabetes Transitioning to Adult Care
NCT05910840Diabetes Mellitus, Diabetes Mellitus, Type 1, Glucose Metabolism Disorders (Including Diabetes Mellitus), Metabolic Disease
Anne-Sophie Brazeau
Not applicable
200
Gatineau, Montreal, Quรฉbec, Sherbrooke
2024-10-07
Recruiting
Combined and Separate Effects of Cannabis and Tobacco: Psychomotor, Subjective and Physiological Outcomes
NCT05526196Driving Under the Influence
DrugCannabis
Centre for Addiction and Mental Health
Not applicable
60
Toronto
2024-10-07
Recruiting
A Study to Compare the Efficacy of Nivolumab and Relatlimab Plus Chemotherapy vs Pembrolizumab Plus Chemotherapy for Stage IV/Recurrent Non-squamous Non-small Cell Lung Cancer With PD-L1 Expression โ‰ฅ 1%
NCT06561386Non-small Cell Lung Cancer
DrugsRelatlimab·Pemetrexed·Nivolumab·Cisplatin
Bristol-Myers Squibb
Phase 3
1,000
Montreal
2024-10-07
Recruiting
A Study to Investigate the Efficacy and Safety of Dato-DXd With or Without Osimertinib Compared With Platinum Based Doublet Chemotherapy in Participants With EGFR-Mutated Locally Advanced or Metastatic Non-Small Cell Lung Cancer
NCT06417814Metastatic Non-small Cell Lung Cancer
DrugsTagrisso·Datopotamab Deruxtecan·Osimertinib·Pemetrexed
AstraZeneca
Phase 3
744
Brampton, Newmarket, Toronto, Montreal, Quรฉbec
2024-10-04
Recruiting
Post Discharge After Surgery Virtual Care with Remote Automated Monitoring Technology-2 (PVC-RAM-2) Trial
NCT04876950Surgery, Perioperative Complication
Population Health Research Institute
Not applicable
2,000
Hamilton
2024-10-04
Recruiting
Behaviour Change for Cancer Survivors Trial
NCT06624930Cancer, Exercise
University of Toronto
Not applicable
236
Toronto
2024-10-03
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Cite this view

Priya Life Science (2026). Clinical trial register: studies with a Canadian investigative site. Derived from ClinicalTrials.gov. Retrieved 28 September 2026. https://priyalifescience.com/clinical-trials-canada?page=26

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About this register

This register is built from ClinicalTrials.gov, the trial registry run by the U.S. National Library of Medicine. It includes every study on the registry that lists at least one investigative site in Canada and is recruiting, not yet recruiting, active but no longer recruiting, or enrolling by invitation: 6,540 studies in total at the last sync on 26 Sep 2026, 19:55 UTC. The full list can be downloaded as CSV or queried as JSON through the register API.

How many clinical trials are recruiting in Canada?

3,515 of the 6,540 studies in this register are recruiting new participants as of the 26 Sep 2026, 19:55 UTC sync. A further 629 have not yet opened recruitment, 2,212 are active but closed to new participants, and 184 are enrolling by invitation only. Eligibility for any study is decided by its study team.

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Browse trials by condition

Breast Cancer (136) Prostate Cancer (110) Cancer (75) Obesity (64) Multiple Myeloma (63) Stroke (57) Heart Failure (56) Ulcerative Colitis (43) Non-small Cell Lung Cancer (39) Type 2 Diabetes (39) Non-Small Cell Lung Cancer (38) Atrial Fibrillation (38) Healthy (36) Anxiety (35) Asthma (35)
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Browse trials by site location

Toronto (2809) Montreal (1902) Vancouver (1179) Calgary (1061) Edmonton (1017) Ottawa (872) London (871) Hamilton (809) Quรฉbec (678) Halifax (533) Winnipeg (455) Sherbrooke (265) Kingston (256) Kelowna (172) Brampton (147)
Listing here is informational and not medical advice; eligibility is determined by each study team. See also the Ireland, UK, EU, USA and China registers.