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Clinical Trials in Canada / NCT07368062
Recruiting Observational

Mental Health After Dexmedetomidine for Electrical Storm

NCT07368062 · tracked via the Priya Life Science Canada tracker
Sponsor
Ottawa Heart Institute Research Corporation
Phase
Observational
Started
2025-03-15
Last updated
2026-07-01

Condition(s) studied

Mental Health

Investigational drug(s) / intervention(s)

Dexmedetomidine →Placebo

Dexmedetomidine: Dexmedetomidine infusion during ICU admission for electrical storm

Placebo: Placebo (standard of care, no dexmedetomidine), for treatment of electrical storm while admitted to ICU

Study summary

The goal of the research study is to measure mental health and quality of life indices of individuals treated for electrical storm (ES). The consequences of being admitted to an intensive care unit (ICU) with electrical storm as well as the treatments patients would have received, are currently not well understood. Understanding the mental health burden of these treatments among survivors can provide insights into how to improve care.

This is a study consisting of patients who participated in the SEDATE trial (dexmedetomidine vs usual standard of care to treat ES in the ICU). Patients who consent to participate in this study will be asked to complete a set of questionnaires 3-6 months after their ICU admission. The purpose of the questionnaires is to measure indices of mental health and health-related quality of life. Each questionnaire will take about 5-15 minutes to complete.

If patients have a scheduled follow-up at the University of Ottawa Heart Institute, a member of the research team will meet with them during their clinic visit to complete the questionnaires. Otherwise, they can be completed over the telephone.

Eligibility

Sex
ALL
Min age
—
Max age
—
Healthy volunteers
No
Inclusion Criteria: * Patients admitted to an intensive care unit with a diagnosis of electrical storm within the preceding 6 months * Previous participants in the SEDATE trial (NCT06281977) Exclusion Criteria: \- None

Primary outcome measure(s)

  • Post-traumatic stress disorder symptoms — Assessed 3-6 months after hospitalization for electrical storm
    Post-traumatic stress disorder (PTSD) checklist (PCL-5) score. Respondents are asked to rate the presence and severity of various symptoms in the preceding month on 5-point Likert scale. A higher score indicates worse symptoms. A cumulative cut-off score of 31-33 is usually considered indicative of probable PTSD

Trial sites (1)

FacilityCityRegionStatus
University of Ottawa Heart Institute Ottawa Ontario Recruiting

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Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07368062 on ClinicalTrials.gov ↗ ← All trials in Canada