Clinical Trials in Brazil / NCT07596979
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Ginger in the Modulation of Inflammatory Cytokines and Oxidative Stress in Patients With Coronary Artery Disease
NCT07596979 · tracked via the Priya Life Science Brazil tracker
Condition(s) studied
Coronary Artery Disease (CAD)Oxidative StressInflammation
Investigational drug(s) / intervention(s)
GingerPlacebo
Ginger: Participants will receive 2 capsules per day, providing the ginger extract daily, at a dosage of 500mg.
Placebo: The placebo group will receive the same amount of 500mg placebo, at the same time, containing corn starch.
Study summary
The study aims to evaluate the effect of ginger supplementation on inflammatory cytokines and markers of oxidative stress in patients with Coronary Artery Disease (CAD). A longitudinal double-blind randomized clinical trial will be carried out, involving CAD participants for two months.
Eligibility
Inclusion Criteria:
* Both sexes
* Over 18 years of age;
* Diagnosed with Coronary Artery Disease: confirmed by coronary angiography, coronary computed tomography angiography, or functional testing with ischemic load);
* Participants who are asymptomatic or have angina limited to functional class III will be considered;
* Patients who have already undergone coronary revascularization and angioplasty may participate;
* the last acute coronary event must have occurred more than one year ago.
Exclusion Criteria:
* Unstable Coronary Artery Disease;
* Pre-operative coronary artery bypass grafting or awaiting elective angioplasty;
* Unstable angina;
* NYHA functional class III or higher;
* Advanced chronic kidney disease (creatinine clearance \< 30 ml/min/1.73 m²);
* Individuals with autoimmune diseases.
Primary outcome measure(s)
- Change of inflammatory status in the participants — Baseline and 8 weeks
Get blood samples to evaluate the supplementation effects in inflammatory biomarkers: interleukin 6 (IL-6), tumor necrosis factor-alpha (TNF-alpha), C-reactive protein (CRP).
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| Denise mafra | Rio de Janeiro | Brazil |
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Official registry record
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07596979 on ClinicalTrials.gov ↗ ← All trials in Brazil