Maintained by Sreepriya Prasannan

MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 — Top 14 finalist

Compiled from ClinicalTrials.gov and CTIS registry records · Last verified 26 Sep 2026 · Editorial standards

At a glance

Zhongshan Ophthalmic Center, Sun Yat-sen University is the lead sponsor of 52 current clinical trials in our China register. 26 are recruiting patients now. The most common phase is Not applicable. The drugs named most often in its trials are Anrikefon, Minocycline and Nalbuphine. The most-studied condition is Myopia.

ClinicalTrials.gov trials by status

Recruiting2650%
Not yet open2140%
Active, closed48%
By invitation12%

Trials by phase

Not applicable2752%
Observational2140%
Phase 424%
Phase 312%
Phase EARLY_PHASE112%

Clinical trials sponsored by Zhongshan Ophthalmic Center, Sun Yat-sen University

52 on ClinicalTrials.gov

Study	Phase	Status	Start	Registers
Efficacy Evaluation of 5-Fluorouracil as an Adjuvant to Endoscopic Dacryocystorhinostomy in Managing Primary Acquired Nasolacrimal Duct Obstruction With Small Lacrimal Sac: A Randomized Controlled Study NCT07154121 · ClinicalTrials.gov ↗ · Primary Acquired Nasolacrimal Duct Obstruction	Not applicable	Recruiting	2025-09	China
Incidence of Glaucoma-related Adverse Events in Pediatric Secondary Intraocular Lens Implantation NCT05136950 · ClinicalTrials.gov ↗ · Lens Implantation, Intraocular	Not applicable	Recruiting	2021-12	China
Evaluation of a County-Based Eye Health Service Model in Rural Chinese Children NCT07547748 · ClinicalTrials.gov ↗ · Myopia, Strabismus, Eye Health	Observational	Recruiting	2025-01	China
Assessing the Impact of Streetscape Exposure on Children's Perception NCT07761949 · ClinicalTrials.gov ↗ · Myopia	Observational	Recruiting	2026-07	China
Biometric Changes After Intervention of Anterior Chamber Angle : an Observational Study NCT06492538 · ClinicalTrials.gov ↗ · Angle-closure Glaucoma, Minimally Invasive Glaucoma Surgery, Goniosynechialysis	Observational	Recruiting	2023-12	China
Development of a Mobile Terminal-Based Intelligent Detection System for Multiple Anterior Segment Diseases of the Eye NCT07634913 · ClinicalTrials.gov ↗ · Artifical Intelligence, Cataract, Pterygium	Observational	Recruiting	2023-12	China
The Impact of 'A Miss Is as Good as a Mile': Is Compensation Necessary for Minimal Ocular Deviation in Myopic Laser Surgery? NCT07512115 · ClinicalTrials.gov ↗ · Myopia, Refractive Ametropia	Not applicable	Recruiting	2026-04	China
Efficacy of Visual and Perceptual Training on Visual Function for Operative Congenital Ectopia Lentis Children NCT07096622 · ClinicalTrials.gov ↗ · Ectopia Lentis, Lens Subluxation or Dislocation	Not applicable	Recruiting	2026-06	China
Comparison of Low- Versus High-Level Angle Kappa Compensation Strategies in SMILE Using the VisuMax 800: A Randomized Clinical Trial NCT07512102 · ClinicalTrials.gov ↗ · Myopia, Refractive Ametropia	Not applicable	Recruiting	2026-04	China
Plasma Biomarker in Amblyopia Patients NCT05705778 · ClinicalTrials.gov ↗ · Amblyopia	Observational	Recruiting	2022-11	China
RCT on Intralesional Rituximab Injection Versus ISRT in Ocular Adnexal MALT Lymphoma NCT06190301 · ClinicalTrials.gov ↗ · Primary Ocular Adnexal MALT Lymphoma Drug: Rituximab	Not applicable	Recruiting	2023-12	China
Impact of Capsular Tension Ring on Intraocular Lens Position in Retinitis Pigmentosa Cataract Patients NCT07126470 · ClinicalTrials.gov ↗ · Cataract, Retinitis Pigmentosa (RP)	Not applicable	Recruiting	2025-08	China
A Prospective Cohort Study on Visual Function and Psychological Conditions Before and After Surgery for Congenital Ptosis NCT07534436 · ClinicalTrials.gov ↗ · Ptosis	Observational	Recruiting	2025-06	China
Efficacy and Safety of Anrikefon for Postoperative Analgesia in Ophthalmic Surgery NCT07269106 · ClinicalTrials.gov ↗ · Ophthalmic Surgery, Postoperative Pain Management, Opioid Analgesia Drugs: Anrikefon, Nalbuphine	Phase 4	Recruiting	2026-01	China
Comparison of PRESBYOND Laser Blended Vision and Conventional Monovision LASIK in Individuals With Presbyopia: A Randomized Clinical Study NCT07512089 · ClinicalTrials.gov ↗ · Presbyopia, Refractive Error	Not applicable	Recruiting	2026-05	China
Follow up Study on Visual Prognosis and Complications of Ectopia Lentis Lens NCT05654025 · ClinicalTrials.gov ↗ · Ectopia Lentis, Dislocation, Lens	Observational	Recruiting	2022-12	China
Choroidal and Retinal Features in PACD and POAG on OCT and OCTA NCT07580014 · ClinicalTrials.gov ↗ · Glaucoma, OCTA, Choroid	Observational	Recruiting	2024-07	China
Evaluation of Chronic Liver Disease Condition and Transplant Prognosis Assisted by Eye Biological Parameters NCT06756009 · ClinicalTrials.gov ↗ · Diagnostic Techniques, Ophthalmological, Liver Transplantation, Liver Cirrhoses	Observational	Recruiting	2022-03	China
The Impact of Surgical Procedures on Postoperative Outcomes in Cataract Phacoemulsification and Analysis of Related Factors NCT07550907 · ClinicalTrials.gov ↗ · Age-related Cataract	Observational	Recruiting	2026-04	China
Comparison of Cytokines Profile in Aqueous Humor and Tear Before and After UCP Treatment NCT06243497 · ClinicalTrials.gov ↗ · Glaucoma, Ultrasound Cyclo Plasty, Aqueous Humor	Observational	Recruiting	2024-02	China
The Cohort Study of Pediatric Cataract NCT05472844 · ClinicalTrials.gov ↗ · Pediatric Cataract	Observational	Recruiting	2022-08	China
The Safety and Efficacy of ZVS106e in the Treatment of IRDs Caused by Biallelic Mutations in ABCA4 NCT07241169 · ClinicalTrials.gov ↗ · Stargardt	Phase EARLY_PHASE1	Recruiting	2025-12	China
Assisting Pulmonary Disease Diagnosis With Ophthalmic Artificial Intelligence Technology NCT05847894 · ClinicalTrials.gov ↗ · Pulmonary Diseases, Ophthalmological Diagnostic Techniques, Artificial Intelligence	Observational	Recruiting	2020-06	China
The Collagen Factors of Rapid Progression of Keratoconus in Children. NCT06722937 · ClinicalTrials.gov ↗ · Keratoconus	Observational	Recruiting	2023-04	China
The Proactive Ophthalmic Examination Cohort NCT05851287 · ClinicalTrials.gov ↗ · Vision Impairment, Eye Diseases	Observational	Recruiting	2023-02	China
Home- vs Hospital-based Care of Anti-VEGF Treatment for Diabetic Macular Edema: Non-inferiority RCT NCT06610747 · ClinicalTrials.gov ↗ · Diabetic Macular Edema	Not applicable	Recruiting	2024-10	China
A Multicenter, Randomized, Double-Blind, Controlled Clinical Study of Minocycline for the Treatment of Retinitis Pigmentosa NCT07082855 · Retinitis Pigmentosa, Inherited Retinal Dystrophy, Retina Disorder Drug: Minocycline	Phase 3	Not yet open	2025-07	China
The Effect of Eyelid Support Plate Assisted Eyelid Massage on Meibomian Gland Dysfunction: a Randomized Controlled Trial NCT07633938 · Dry Eye Disease (DED), MGD-Meibomian Gland Dysfunction	Not applicable	Not yet open	2026-07	China
Comparison of Early Postoperative Visual Acuity Between Intracapsular and Supracapsular Phacoemulsification: A Randomized Controlled Clinical Trial NCT07407049 · ClinicalTrials.gov ↗ · Cataract	Not applicable	Not yet open	2026-02	China
The Effects of Glasses-Free 3D Training on Visual and Cognitive Function in Presbyopic Individuals NCT06853691 · ClinicalTrials.gov ↗ · Presbyopia	Not applicable	Not yet open	2025-02	China
AI-Assisted Structured Guidance for Narrative Review Writing NCT07618819 · ClinicalTrials.gov ↗ · AI-Assisted Academic Writing, Medical Education, Narrative Review Writing	Not applicable	Not yet open	2026-06	China
Effective Dose of Alfentanil Combined With Propofol for Laryngeal Mask Airway Insertion in Children NCT07581665 · ClinicalTrials.gov ↗ · Pediatric Anesthesia, Airway Management, General Anesthesia	Phase 4	Not yet open	2026-05	China
Exploring the Interaction Between Metabolic Disorders and NLPR3 Inflammasome Activation in DR Inflammatory Damage NCT06272565 · ClinicalTrials.gov ↗ · Diabetic Retinopathy, Diabetic Macular Edema, Anti-vascular Endothelial Growth Factor	Observational	Not yet open	2024-07	China
Clinical and Subclinical Keratoconus Cohort Study NCT07553832 · ClinicalTrials.gov ↗ · Keratoconus	Observational	Not yet open	2026-09	China
Productivity Study of Presbyopia Improvement in Textile Workers NCT04172935 · ClinicalTrials.gov ↗ · Presbyopia	Not applicable	Not yet open	2019-12	China
Effect of Different Needle Insertion Positions on the Clinical Outcomes of YAMANE Technique NCT07446829 · ClinicalTrials.gov ↗ · Congenital Ectopia Lentis	Not applicable	Not yet open	2026-02	China
Effect of Light-Blocking Lenses on Pediatric Hyperopia NCT07142915 · ClinicalTrials.gov ↗ · Hyperopia	Not applicable	Not yet open	2025-08	China
Effect of a Myopia Prediction System on Myopia Prevention and Control NCT06633393 · ClinicalTrials.gov ↗ · Myopia, Randomized Controlled Trials, Artificial Intelligence (AI)	Not applicable	Not yet open	2024-11	China
Comparison of Two Rotational Alignment Methods for Astigmatism Correction in SMILE Surgery NCT07696468 · ClinicalTrials.gov ↗ · Myopia, Refractive Ametropia	Not applicable	Not yet open	2026-07	China
Survey of Sensory Impairment Indicators Among Adults Aged 65 Years and Older in Xinxing County NCT07694505 · ClinicalTrials.gov ↗ · Visual Impairment, Hearing Loss, Dual Sensory Impairment	Observational	Not yet open	2026-07	China
Influence of Different Needle Insertion Positions on the Clinical Efficacy of Suture-Fixated Transscleral IOL Implantation Without Knots NCT07252349 · ClinicalTrials.gov ↗ · Congenital Ectopia Lentis	Not applicable	Not yet open	2025-12	China
Multimodal Biomarkers in Prediction of Diabetic Retinopathy NCT07098832 · ClinicalTrials.gov ↗ · Diabetic Retinopathy (DR)	Observational	Not yet open	2025-07	China
Cohort Study on Refractive Errors in Preschool Children NCT07706218 · ClinicalTrials.gov ↗ · Refractive Errors	Observational	Not yet open	2026-08	China
An Interpretable Fundus Diseases Report Generating System Based On Weakly Labelings NCT06918028 · ClinicalTrials.gov ↗ · Retinal Diseases, Choroidal Disease, Pathological Myopia	Observational	Not yet open	2025-05	China
Effect of Light-Blocking Lenses on Hyperopic Anisometropic Children NCT07142928 · ClinicalTrials.gov ↗ · Anisometropia, Hyperopia	Not applicable	Not yet open	2025-08	China
A Study of Full-Spectrum Screen Lighting for Reducing Screen-Related Eye Fatigue and Dry Eye NCT07706231 · ClinicalTrials.gov ↗ · Visual Fatigue, Dry Eye, Computer Vision Syndrome	Not applicable	Not yet open	2026-09	China
Donors Predisposed by Corneal Collagen Cross-linking in Deep Lamellar Keratoplasty for the Patients With Keratoconus NCT05905978 · ClinicalTrials.gov ↗ · Keratoconus	Not applicable	Not yet open	2023-06	China
Evaluating App-Based Vision Testing (WHOeyes) Combined With the Questionnaire as a Substitute for One-Week Postoperative In-Clinic Follow-Up in Age-Related Cataract Patients: A Multi-center Randomized Controlled Trial NCT06429527 · ClinicalTrials.gov ↗ · Cataract Senile	Not applicable	By invitation	2024-12	China
Evaluation of the Safety and Efficacy of the D.D.C Dual-control Technology Spectacle Lenses in Delaying the Progression of Myopia: a Randomized Controlled Trial NCT07264361 · ClinicalTrials.gov ↗ · Myopia, Progressive	Not applicable	Active, closed	2026-03	China
Safety and Efficacy of Blue Star MAX-5 Lenses in Myopia Control NCT06647160 · ClinicalTrials.gov ↗ · Myopia, Progressive	Not applicable	Active, closed	2024-11	China
Orthokeratology and 0.01% Atropine Sequential Treatment for Myopia Control NCT06667037 · ClinicalTrials.gov ↗ · Myopia	Not applicable	Active, closed	2024-09	China
Effect of Mobile Communication on Congenital Ectopia Lentis Follow-up Adherence NCT05628129 · ClinicalTrials.gov ↗ · Ectopia Lentis	Not applicable	Active, closed	2022-12	China

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.

Drugs in Zhongshan Ophthalmic Center, Sun Yat-sen University trials

4 compounds

Drugs and biologicals named as interventions in these trials, with the number of this sponsor's trials that name each one. Placebos and generic comparators are excluded.

Anrikefon1 Minocycline1 Nalbuphine1 Rituximab1

Conditions in Zhongshan Ophthalmic Center, Sun Yat-sen University trials

77 conditions

Myopia7 Cataract4Presbyopia3Keratoconus3Refractive Ametropia3Ectopia Lentis3Diabetic Retinopathy2 Diabetic Macular Edema2Congenital Ectopia Lentis2Myopia, Progressive2Hyperopia2Glaucoma2 Retinitis Pigmentosa1Inherited Retinal Dystrophy1Retina Disorder1Dry Eye Disease (DED)1MGD-Meibomian Gland Dysfunction1Primary Acquired Nasolacrimal Duct Obstruction1Lens Implantation, Intraocular1Strabismus1Eye Health1AI-Assisted Academic Writing1Medical Education1Narrative Review Writing1

By trial register

Register	Trials	Recruiting
Clinical trials in China	52	26

A trial with sites in more than one country appears in each of those registers.

Other sponsors in Myopia

Sponsor	Trials
Shanghai Eye Disease Prevention and Treatment Center	13
SightGlass Vision	8
Beijing Tongren Hospital	6
Ruihua Wei	4
CooperVision International Limited (CVIL)	3
nthalmic	3
Beijing Visionly Plus Eye Hospital	3
Essilor International	2
Tianjin Eye Hospital	2
Zhaoke (Guangzhou) Ophthalmology Pharmaceutical	2

Sponsors with the most current trials registered for this condition.

Questions about Zhongshan Ophthalmic Center, Sun Yat-sen University trials

How many clinical trials does Zhongshan Ophthalmic Center, Sun Yat-sen University sponsor?

Zhongshan Ophthalmic Center, Sun Yat-sen University is the lead sponsor of 52 current trials on ClinicalTrials.gov in our China register, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are Zhongshan Ophthalmic Center, Sun Yat-sen University trials recruiting?

Yes. 26 of its 52 ClinicalTrials.gov trials are recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Which drugs is Zhongshan Ophthalmic Center, Sun Yat-sen University testing?

Its current trials name 4 drugs and biologicals as interventions. The most frequent are Anrikefon (1), Minocycline (1), Nalbuphine (1) and Rituximab (1). The number in brackets is how many of its trials name each drug.

Where does this information come from?

Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.

How this page is built

Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.

ClinicalTrials.gov (U.S. National Library of Medicine) ↗ Trial IDs, titles, lead sponsor, phase, overall status, start date, conditions and intervention names
EU Clinical Trials Information System (CTIS) ↗ EU trial numbers, titles, sponsor, phase, status, therapeutic area and member-state countries

This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.

Zhongshan Ophthalmic Center, Sun Yat-sen University clinical trials