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Adverum Biotechnologies clinical trials

Source: ClinicalTrials.gov, U.S. National Library of Medicine — current trials in our USA and UK registers with Adverum Biotechnologies as lead sponsor. Synced 26 Sep 2026
6Current trials
2Recruiting now
1Drug in these trials
2Trial registers
Maintained by Sreepriya Prasannan
MSc Digital Transformation of Life Sciences (Innopharma Education / Griffith College); MSc & BSc Botany HSE Spark Ignite 2026 — Top 14 finalist
Compiled from ClinicalTrials.gov and CTIS registry records · Last verified · Editorial standards
At a glance

Adverum Biotechnologies is the lead sponsor of 6 current clinical trials in our USA and UK registers. 2 are recruiting patients now. The most common phase is Phase 2. The drugs named most often in its trials are Aflibercept. The most-studied condition is Neovascular Age-related Macular Degeneration.

ClinicalTrials.gov trials by status

  • Recruiting233%
  • Active, closed467%

Trials by phase

  • Phase 2233%
  • Observational233%
  • Phase 3233%
01

Clinical trials sponsored by Adverum Biotechnologies

6 on ClinicalTrials.gov
StudyPhaseStatusStartRegisters
Ixoberogene Soroparvovec (Ixo-vec) Contralateral Dosing Study in Participants With Neovascular Age-related Macular Degeneration
NCT07630649 · Neovascular Age-Related Macular Degeneration (nAMD) Wet AMD
Phase 2 Recruiting 2026-06 USA
Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-related Macular Degeneration (AQUARIUS)
NCT07482176 · ClinicalTrials.gov ↗ · Neovascular Age-Related Macular Degeneration (nAMD), Wet AMD
Phase 3 Recruiting 2026-03 USA
Safety and Efficacy of ADVM-022 in Treatment-Experienced Patients With Neovascular Age-related Macular Degeneration [LUNA]
NCT05536973 · Neovascular Age-related Macular Degeneration
Phase 2 Active, closed 2022-08 UK, USA
Long-Term Follow-up Study of ADVM-022 in DME (INFINITY-EXT)
NCT05607810 · Diabetic Macular Edema, Diabetic Retinopathy
Observational Active, closed 2022-08 USA
Efficacy and Safety Study of Ixoberogene Soroparvovec (Ixo-vec) in Participants With Neovascular Age-Related Macular Degeneration
NCT06856577 · ClinicalTrials.gov ↗ · Neovascular Age-Related Macular Degeneration (nAMD), Wet AMD
Phase 3 Active, closed 2025-02 USA
Long-term Study of ADVM-022 in Neovascular (Wet) AMD [OPTIC-EXT]
NCT04645212 · ClinicalTrials.gov ↗ · Wet Age-related Macular Degeneration, Neovascular Age-related Macular Degeneration
Observational Active, closed 2020-12 USA

Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Titles and statuses are copied from the registry as published.

02

Drugs in Adverum Biotechnologies trials

1 compound

Drugs and biologicals named as interventions in these trials, with the number of this sponsor's trials that name each one. Placebos and generic comparators are excluded.

03

Conditions in Adverum Biotechnologies trials

7 conditions
Neovascular Age-related Macular Degeneration2Neovascular Age-Related Macular Degeneration (nAMD)2Wet AMD2Diabetic Macular Edema1Diabetic Retinopathy1Neovascular Age-Related Macular Degeneration (nAMD) Wet AMD1Wet Age-related Macular Degeneration1
04

By trial register

RegisterTrialsRecruiting
Clinical trials in USA62
Clinical trials in UK10

A trial with sites in more than one country appears in each of those registers.

05

Other sponsors in Neovascular Age-related Macular Degeneration

SponsorTrials
Innostellar Biotherapeutics2
Ocular Therapeutix1

Sponsors with the most current trials registered for this condition.

06

Questions about Adverum Biotechnologies trials

How many clinical trials does Adverum Biotechnologies sponsor?

Adverum Biotechnologies is the lead sponsor of 6 current trials on ClinicalTrials.gov in our USA and UK registers, as of the registry sync on 26 September 2026. Completed and withdrawn studies are not counted.

Are Adverum Biotechnologies trials recruiting?

Yes. 2 of its 6 ClinicalTrials.gov trials are recruiting. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.

Which drugs is Adverum Biotechnologies testing?

Its current trials name 1 drug or biological as interventions. The most frequent are Aflibercept (2). The number in brackets is how many of its trials name each drug.

Where does this information come from?

Every trial, status, phase and condition on this page is copied from public ClinicalTrials.gov and EU CTIS records by a daily sync, grouped by the sponsor name each registry records. It says nothing about the organisation beyond its registered trials, and it is not medical advice.

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How this page is built

Everything on this page is copied from public registry records — it is not written from memory, and nothing here describes the organisation beyond its registered trials. Each trial links to its own record so you can check it yourself.

This page is built automatically: a daily sync job reads the registry records behind our trial registers and groups every current trial by its lead sponsor name, ignoring legal-form suffixes such as Inc. or Ltd. A small, hand-checked list joins the same organisation's different registry names (for example its EU legal entity). There is no AI drafting and no per-sponsor editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The the registries data on this page was last retrieved on 26 Sep 2026.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.