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Regulatory · NICE technology appraisal guidance · England

NICE technology appraisals

Every medicine and treatment NICE has appraised for the NHS in England since 2000: NICE's recommendation, when it was published, whether it still stands, and a link to the guidance and to the medicine's trials on this site.

Source: NICE technology appraisal guidance and NICE's appraisal recommendations data, shown with NICE's permission. Checked 9 Nov 2026
1,195Technology appraisals published
90%Of 903 current decided appraisals recommend for at least some patients
78Published in 2026 so far
984Linked to a medicine page here

NICE has published 1,195 technology appraisals since 2000, and 1,068 of them are still current. Of the current appraisals where NICE reached a decision, 90% recommend the medicine or treatment for at least some patients, including through the Cancer Drugs Fund. The most recent is TA1195, published 30 Sep 2026. NICE's decisions apply to the NHS in England; in Ireland the HSE decides on reimbursement, advised by the National Centre for Pharmacoeconomics.

01

What NICE decided

Appraisals by recommendation type
  • Recommended: the NHS in England should fund it for the use it is licensed for.
  • Optimised: recommended, but for a narrower group of patients than the licence covers.
  • Cancer Drugs Fund / Innovative Medicines Fund: funded for a limited period while more evidence is collected.
  • Only in research: to be used only as part of a study.
  • Not recommended: NICE decided the NHS should not fund it for this use.
  • Terminated: the company did not send evidence, so NICE could not make a recommendation.

An appraisal can contain several recommendations, for different groups of patients, so it can appear under more than one type. These explanations are ours; NICE's own definitions are on nice.org.uk.

02

Appraisals matching “Everolimus”

9 appraisals, newest first
AppraisalMedicine pageNICE recommendationPublishedStatus
Lenvatinib with everolimus for previously treated advanced renal cell carcinoma
NICE TA498
LenvatinibRecommended24 Jan 2018Current
Immunosuppressive therapy for kidney transplant in children and young people
NICE TA482
Basiliximab, Mycophenolate Mofetil, Tacrolimus, Sirolimus, Everolimus, BelataceptRecommended Not recommended11 Oct 2017Current
Immunosuppressive therapy for kidney transplant in adults
NICE TA481
Basiliximab, Mycophenolate Mofetil, Tacrolimus, Sirolimus, Everolimus, BelataceptRecommended Not recommended11 Oct 2017Current
Everolimus and sunitinib for treating unresectable or metastatic neuroendocrine tumours in people with progressive disease
NICE TA449
Everolimus, SunitinibRecommended28 Jun 2017Current
Everolimus for advanced renal cell carcinoma after previous treatment
NICE TA432
EverolimusRecommended22 Feb 2017Current
Everolimus with exemestane for treating advanced breast cancer after endocrine therapy
NICE TA421
EverolimusRecommended21 Dec 2016Current
Everolimus for preventing organ rejection in liver transplantation
NICE TA348
EverolimusNot recommended22 Jul 2015Current
Everolimus in combination with exemestane for treating advanced HER2-negative hormone-receptor-positive breast cancer after endocrine therapy
NICE TA295
EverolimusNot recommended28 Aug 2013Current
Everolimus for the second-line treatment of advanced renal cell carcinoma
NICE TA219
EverolimusNot recommended19 Apr 2011Replaced by TA432

Titles link to the guidance on nice.org.uk, where the full recommendations are. A medicine is linked to its page here only when the name NICE appraised is exactly the same molecule as ours; medicines given alongside it (“with chemotherapy”) are not counted as appraised. Appraisals of devices and procedures are listed but have no medicine page.

© NICE 2026 technology appraisal guidance. Available from www.nice.org.uk/guidance. All rights reserved. Subject to Notice of rights. NICE guidance is prepared for the National Health Service in England. All NICE guidance is subject to regular review and may be updated or withdrawn. NICE accepts no responsibility for the use of its content in this product/publication.

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How this page is built

NICE has allowed us to show the appraisal number, title, recommendation category and dates of each technology appraisal, with a link to the guidance. No guidance text is reproduced.

A nightly job reads NICE's recommendations data, reads each new appraisal page once and re-checks every page every 60 days for replaced or withdrawn guidance. It keeps the previous version if a refresh fails. No AI drafting. See our methodology. The NICE data on this page was last retrieved on 9 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.

Please verify before you rely on this. This page is general information for life-science and pharmaceutical professionals. It is not medical advice, and it has not been reviewed by a clinician — our editorial team holds life-science qualifications, not clinical ones. It is not exhaustive and may not reflect the most recent label change. Always check the official prescribing information (US Prescribing Information or EU SmPC) and speak to your doctor or pharmacist before acting on anything here. Drugs in the same class are not automatically interchangeable, and approvals, brand names and indications differ between the US, the EU/Ireland (EMA/HPRA) and other regions. Spotted an error? Tell us — we correct promptly and log it.