IXPRIM effervescent 37.5 mg/325 mg effervescent tablets
Authorisation PA2242/006/002 · Grunenthal Pharma Limited.
- Licence holder
- Grunenthal Pharma Limited. (all products →)
- Active substances
- Paracetamol, Tramadol hydrochloride
- Clinical trials
- 20 clinical trials → 8 clinical trials →
- Dosage form
- Effervescent tablet
- Route of administration
- Oral use
- ATC codes
- N02AJ, N02AJ13
- First authorised
- 12/12/2008
- Prescription status
- Product subject to prescription which may not be renewed (A)
- Supply
- Supply through pharmacies only
- Legal basis
- Fixed combination application (Article 10b of Directive No 2001/83/EC)
Paracetamol: supply and approvals
155 authorised products on the HPRA list contain Paracetamol. Shortage records below are for the substance in the EU, US and German markets and may not affect this Irish product; for Irish supply, check with the HPRA or a pharmacist.
- EU shortage (EMA)
- No entry in the EMA shortage catalogue (checked 7 Oct 2026)
- US shortage (FDA)
- No entry in the FDA drug shortage list (checked 7 Oct 2026)
- Germany (BfArM)
- 1 supply notice, e.g. Azur compositum (16 Aug 2023 to 30 Dec 2026)
Registers: EU shortages · US shortages · German shortages · EMA approvals
Tramadol hydrochloride: supply and approvals
21 authorised products on the HPRA list contain Tramadol hydrochloride. Shortage records below are for the substance in the EU, US and German markets and may not affect this Irish product; for Irish supply, check with the HPRA or a pharmacist.
- EU shortage (EMA)
- No entry in the EMA shortage catalogue (checked 7 Oct 2026)
- US shortage (FDA)
- No entry in the FDA drug shortage list (checked 7 Oct 2026)
- Germany (BfArM)
- No entry in the BfArM supply notices (checked 7 Oct 2026)
Registers: EU shortages · US shortages · German shortages · EMA approvals
This listing is regulatory information, not medical advice — consult the package leaflet, SPC, or a healthcare professional. For the authoritative record see the HPRA register.
How this page is built
The facts on this page are pulled directly from the HPRA's (Health Products Regulatory Authority) official open dataset — they are not written from memory, and nothing here is summarised or edited. Each field below names the dataset it came from, so you can check it yourself.
- HPRA Authorised Medicines List (open data) ↗ Licence number, holder, active substance(s), dosage form, route, ATC code(s), authorisation date and prescription status for this product
This page is built automatically: a daily sync job downloads HPRA's published XML export and copies the licence number, holder, active substance(s), dosage form, route, ATC code(s), authorisation date and prescription status directly into this page — no AI drafting and no per-product editorial pass. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The HPRA data on this page was last retrieved on 8 Oct 2026. How every register is built: methodology · fixes we have made: corrections log.