Tizanidine clinical trials
Tizanidine is named as an intervention in 2 current clinical trials in our Egypt register. 1 is recruiting patients now. All registered phases are Not applicable. The sponsor with the most trials is Beni-Suef University (1). The most-studied condition is Airway Management.
Where Tizanidine is approved
All regulators →Of the three regulators tracked here, the first to approve Tizanidine was the US, on 27 Nov 1996. It is approved in 2 of the 3 regulators tracked here.
From the regulators' own registers: FDA Drugs@FDA, the EMA medicines list and Health Canada's Notice of Compliance database. Dates are the first listed approval of a product containing only this substance; combination products and nationally authorised EU medicines are not counted.
Tizanidine patents and exclusivity
Expiry tracker →Protections still running for marketed products containing Tizanidine, as listed by the regulators. Expired patents and exclusivities, and discontinued products, are not shown.
- 2 listed patents; the last listed expires 7 May 2042 (US 12263158).
Reproduced from the FDA Orange Book and Purple Book (checked 8 Nov 2026) and the European Commission's Union Register of medicinal products (CC BY 4.0; the EU expiry date is calculated exactly as the Commission's register displays it). Listed patents and dates are as submitted to or published by the regulator and may not reflect litigation, invalidation, settlements, lapsed fees or later extensions. This is not legal advice or a freedom-to-operate opinion, and it does not say when a generic or biosimilar will launch.
What health systems spend on Tizanidine
All medicines →From NHSBSA Prescription Cost Analysis (Open Government Licence v3.0) and CMS State Drug Utilization Data. Both are gross amounts: neither system publishes its discounts or rebates per drug. Products combining several substances are not counted here.
Patient leaflets for Tizanidine
The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.
- IEIreland: 6 products on the HPRA listEach product record links to the HPRA, which publishes the leaflet and SmPC.
- UKUnited Kingdom: Search MHRA ProductsPatient information leaflets and SmPCs for UK-licensed products.
- USUnited States: Search DailyMedFDA-approved labels, including patient and medication guides.
Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.
Trials by status
Trials by phase
Clinical trials of Tizanidine
2 trials| Study | Phase | Status | Lead sponsor | Registers |
|---|---|---|---|---|
|
The Effect of Preoperative Administration of Oral Tizanidine on the Postoperative Pain and Sleep Quality
NCT07800364 · The Effect of Preoperative Administration of Oral Tizanidine, Post Operative Pain
|
Not applicable | Recruiting | Tanta University | Egypt |
|
Tizanidine Premedication Versus Placebo for Laryngeal Mask Airway Insertion and Recovery in Adults Undergoing Ambulatory Surgery
NCT07921602 · ClinicalTrials.gov ↗ · Airway Management
|
Not applicable | Not yet open | Beni-Suef University | Egypt |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
Tizanidine across our data
Ireland · EU · USThe same active substance in our other registers, matched by its exact name. Each entry links to the register record it comes from.
Licensed in Ireland (HPRA)
6 single-substance products containing Tizanidine on the HPRA medicines list.
- Zanaflex 2 mg TabletsTeva Pharma B.V. · PA0749/054/001 · Marketed
- Zanaflex 4 mg TabletsTeva Pharma B.V. · PA0749/054/002 · Marketed
- Zanaflex 2 mg TabletsPCO Manufacturing Ltd. · PPA0465/474/001
- Zanaflex 2 mg TabletsIMED Healthcare Ltd. · PPA1463/224/001
- Zanaflex 4 mg TabletsPCO Manufacturing Ltd. · PPA0465/474/002
Supply shortages
No entry for Tizanidine in the EMA, FDA or German BfArM shortage lists we track.
Conditions studied with Tizanidine
3 conditionsSponsors
lead sponsor per trial| Lead sponsor | Trials |
|---|---|
| Beni-Suef University | 1 |
| Tanta University | 1 |
By country register
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in Egypt | 2 | 1 |
A trial with sites in more than one country appears in each of those registers.
Questions about Tizanidine trials
How many clinical trials are testing Tizanidine?
2 current trials in our Egypt register name Tizanidine as a drug or biological intervention, as of the registry sync on 8 November 2026. Completed and withdrawn studies are not counted.
Are Tizanidine trials recruiting patients?
Yes. 1 of the 2 trials is recruiting: 1 with sites in Egypt. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Who sponsors Tizanidine clinical trials?
Beni-Suef University (1) and Tanta University (1). The number in brackets is how many trials each organisation leads.
Is Tizanidine licensed in Ireland?
Yes. The HPRA medicines list includes 6 single-substance products containing Tizanidine, for example Zanaflex 2 mg Tablets (Teva Pharma B.V.). A licence does not mean a product is currently marketed or reimbursed; see each product's record.
Is there a Tizanidine shortage?
Not in the lists we track: Tizanidine has no entry in the EMA, FDA or German BfArM shortage registers as of their latest sync.
Where does this information come from?
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Tizanidine works or whether it is effective, and it is not medical advice.
How this page is built
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Tizanidine works or whether it is effective. Each trial links to its own record so you can check it yourself.
- ClinicalTrials.gov (U.S. National Library of Medicine) ↗ Trial IDs, titles, intervention names and synonyms, phase, overall status, lead sponsor and conditions for every trial on this page
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Tizanidine (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 8 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.