Minocycline hydrochloride clinical trials
Minocycline hydrochloride is named as an intervention in 4 current clinical trials in our China register. 4 are recruiting patients now. The most common phase is Phase 3. The sponsor with the most trials is Beijing Tiantan Hospital (2). The most-studied condition is Acute Ischemic Stroke.
Where Minocycline hydrochloride is approved
All regulators →Of the three regulators tracked here, the first to approve Minocycline hydrochloride was the US, on 30 Jun 1971. It is approved in 2 of the 3 regulators tracked here.
From the regulators' own registers: FDA Drugs@FDA, the EMA medicines list and Health Canada's Notice of Compliance database. Dates are the first listed approval of a product containing only this substance; combination products and nationally authorised EU medicines are not counted.
Minocycline hydrochloride patents and exclusivity
Expiry tracker →Protections still running for marketed products containing Minocycline hydrochloride, as listed by the regulators. Expired patents and exclusivities, and discontinued products, are not shown.
- 24 listed patents; the last listed expires 7 Jan 2039 (US 11364212).
- Exclusivity NP: New product, until 1 Nov 2027.
Reproduced from the FDA Orange Book and Purple Book (checked 8 Nov 2026) and the European Commission's Union Register of medicinal products (CC BY 4.0; the EU expiry date is calculated exactly as the Commission's register displays it). Listed patents and dates are as submitted to or published by the regulator and may not reflect litigation, invalidation, settlements, lapsed fees or later extensions. This is not legal advice or a freedom-to-operate opinion, and it does not say when a generic or biosimilar will launch.
What health systems spend on Minocycline hydrochloride
All medicines →From NHSBSA Prescription Cost Analysis (Open Government Licence v3.0) and CMS State Drug Utilization Data. Both are gross amounts: neither system publishes its discounts or rebates per drug. Products combining several substances are not counted here.
How Minocycline hydrochloride works
All drug targets →- Bacterial 70S ribosome inhibitor InhibitorChEMBL only
- Cognitive impairmentPhase 3
- Peri-ImplantitisPhase 3
- Amyotrophic lateral sclerosisPhase 3
- Bipolar disorderPhase 3
- Cognitive disorderPhase 3
- Depressive disorderPhase 3
- Familial spontaneous pneumothoraxPhase 3
- Hypertensive disorderPhase 3
- Idiopathic pulmonary fibrosisPhase 3
- Intracerebral hemorrhagePhase 3
Mechanisms and diseases from ChEMBL via the Open Targets Platform (release 26.09), ChEMBL record CHEMBL1434, CC BY-SA 3.0. Targets checked against the IUPHAR/BPS Guide to PHARMACOLOGY (2026.3.1), ligand 10831, CC BY-SA 4.0. Trial phases are not approvals: approved uses are shown from the regulators' own records where we hold them.
Patient leaflets for Minocycline hydrochloride
The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.
- IEIreland: 2 products on the HPRA listEach product record links to the HPRA, which publishes the leaflet and SmPC.
- UKUnited Kingdom: Search MHRA ProductsPatient information leaflets and SmPCs for UK-licensed products.
- USUnited States: Search DailyMedFDA-approved labels, including patient and medication guides.
Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.
Reference identifiers for Minocycline hydrochloride
- ChEMBL
- CHEMBL1434
- DrugBank
- DB01017
- PubChem CID
- 51537604
- CAS number
- 10118-90-8
- FDA UNII
- FYY3R43WGO
- Wikidata
- Q415336
- Wikipedia
- Minocycline
Codes that identify this medicine in other databases, from Wikidata (CC0), matched by its ChEMBL ID. The ATC code is the WHO classification of what the medicine is used for.
Trials by status
Trials by phase
Clinical trials of Minocycline hydrochloride
4 trials| Study | Phase | Status | Lead sponsor | Registers |
|---|---|---|---|---|
|
Efficacy and Safety of Minocycline in Acute Spontaneous Intracerebral Hemorrhage
NCT07338175 · ClinicalTrials.gov ↗ · Intracerebral Hemorrhage
|
Phase 3 | Recruiting | Beijing Tiantan Hospital | China |
|
Efficacy and Safety of Minocycline in Patients With Acute Ischaemic Stroke Receiving Intravenous Thrombolysis
NCT07526987 · ClinicalTrials.gov ↗ · Ischaemic Stroke
|
Phase 3 | Recruiting | Beijing Tiantan Hospital | China |
|
Minocycline After Successful Endovascular Thrombectomy Recanalization in Posterior Circulation Arterial Occlusion (ATTRACTION-MINOP)
NCT07594301 · ClinicalTrials.gov ↗ · Acute Ischemic Stroke, Endovascular Thrombectomy, Minocycline
|
Phase 2/3 | Recruiting | Xiang Luo | China |
|
Minocycline After Successful Endovascular Thrombectomy Recanalization in Acute Anterior Circulation Large Vessel Occlusion (ATTRACTION-MINOA)
NCT07594314 · ClinicalTrials.gov ↗ · Acute Ischemic Stroke, Vessel Occlusion, Endovascular Thrombectomy
|
Phase 2/3 | Recruiting | Xiang Luo | China |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
Conditions studied with Minocycline hydrochloride
8 conditionsSponsors
lead sponsor per trial| Lead sponsor | Trials |
|---|---|
| Beijing Tiantan Hospital | 2 |
| Xiang Luo | 2 |
By country register
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in China | 4 | 4 |
A trial with sites in more than one country appears in each of those registers.
Related compounds
Questions about Minocycline hydrochloride trials
How many clinical trials are testing Minocycline hydrochloride?
4 current trials in our China register name Minocycline hydrochloride as a drug or biological intervention, as of the registry sync on 8 November 2026. Completed and withdrawn studies are not counted.
Are Minocycline hydrochloride trials recruiting patients?
Yes. 4 of the 4 trials are recruiting: 4 with sites in China. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Who sponsors Minocycline hydrochloride clinical trials?
Beijing Tiantan Hospital (2) and Xiang Luo (2). The number in brackets is how many trials each organisation leads.
Where does this information come from?
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Minocycline hydrochloride works or whether it is effective, and it is not medical advice.
How this page is built
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Minocycline hydrochloride works or whether it is effective. Each trial links to its own record so you can check it yourself.
- ClinicalTrials.gov (U.S. National Library of Medicine) ↗ Trial IDs, titles, intervention names and synonyms, phase, overall status, lead sponsor and conditions for every trial on this page
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Minocycline hydrochloride (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 8 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.