Doxapram clinical trials
Doxapram is named as an intervention in 2 current clinical trials in our Netherlands, Belgium, Canada and Egypt registers. 2 are recruiting patients now. The most common phase is Phase 3. The sponsor with the most trials is Erasmus Medical Center (1). The most-studied condition is Apnea of Prematurity.
Where Doxapram is approved
All regulators →Of the three regulators tracked here, the first to approve Doxapram was the US, on 23 Jun 1965.
From the regulators' own registers: FDA Drugs@FDA, the EMA medicines list and Health Canada's Notice of Compliance database. Dates are the first listed approval of a product containing only this substance; combination products and nationally authorised EU medicines are not counted.
What health systems spend on Doxapram
All medicines →From NHSBSA Prescription Cost Analysis (Open Government Licence v3.0) and CMS State Drug Utilization Data. Both are gross amounts: neither system publishes its discounts or rebates per drug. Products combining several substances are not counted here.
How Doxapram works
All drug targets →- Potassium channel subfamily K member 3 blocker BlockerTarget: KCNK3 potassium two pore domain channel subfamily K member 3ChEMBL only
- Potassium channel subfamily K member 9 blocker BlockerTarget: KCNK9 potassium two pore domain channel subfamily K member 9ChEMBL only
- BradycardiaPhase 3
- HypoxemiaPhase 3
- Bronchopulmonary dysplasiaPhase 3
Mechanisms and diseases from ChEMBL via the Open Targets Platform (release 26.09), ChEMBL record CHEMBL1754, CC BY-SA 3.0. Targets checked against the IUPHAR/BPS Guide to PHARMACOLOGY (2026.3.1), ligand 7169, CC BY-SA 4.0. Trial phases are not approvals: approved uses are shown from the regulators' own records where we hold them.
Patient leaflets for Doxapram
The package leaflet is the official guide for patients that comes with every medicine. These links go to the regulators that publish it.
- IEIreland: 2 products on the HPRA listEach product record links to the HPRA, which publishes the leaflet and SmPC.
- UKUnited Kingdom: Search MHRA ProductsPatient information leaflets and SmPCs for UK-licensed products.
- USUnited States: Search DailyMedFDA-approved labels, including patient and medication guides.
Leaflets differ between brands and countries; always read the one that comes with your own medicine. This is regulatory information, not medical advice.
Reference identifiers for Doxapram
- ATC code
- R07AB01
- ChEMBL
- CHEMBL1754
- DrugBank
- DB00561
- PubChem CID
- 3156
- CAS number
- 309-29-5
- FDA UNII
- 94F3830Q73
- Wikidata
- Q737743
- Wikipedia
- Doxapram
Codes that identify this medicine in other databases, from Wikidata (CC0), matched by its ChEMBL ID. The ATC code is the WHO classification of what the medicine is used for.
Trials by status
Trials by phase
Clinical trials of Doxapram
2 trials| Study | Phase | Status | Lead sponsor | Registers |
|---|---|---|---|---|
|
Doxapram Therapy in Preterm Infants (DOXA Trial)
NCT04430790 · Apnea of Prematurity, Respiratory Insufficiency
|
Phase 3 | Recruiting | Erasmus Medical Center | Netherlands, Belgium, Canada |
|
Doxapram Administration on Diaphragmatic Excursion in Mechanically Ventilated Patients With Chronic Obstructive Pulmonary Disease Undergoing Spontaneous Breathing Trial
NCT07022704 · ClinicalTrials.gov ↗ · COPD, Mechanical Ventilation, Weaning From Mechanical Ventilation
|
Observational | Recruiting | Cairo University | Egypt |
Registers list studies that are recruiting, about to open, active but closed to enrolment, or enrolling by invitation. The UK and USA registers cover industry-sponsored studies only. Trial titles and statuses are copied from the registry as published.
Doxapram across our data
Ireland · EU · USThe same active substance in our other registers, matched by its exact name. Each entry links to the register record it comes from.
Licensed in Ireland (HPRA)
2 single-substance products containing Doxapram on the HPRA medicines list.
- Doxapram Hydrochloride 20mg/ml Solution for InjectionMercuryPharm Ltd · PA0857/003/002 · Marketed
- Doxapram Hydrochloride 2mg/ml Solution for InfusionMercuryPharm Ltd · PA0857/003/001 · Not marketed
Supply shortages
No entry for Doxapram in the EMA, FDA or German BfArM shortage lists we track.
Conditions studied with Doxapram
5 conditionsSponsors
lead sponsor per trial| Lead sponsor | Trials |
|---|---|
| Erasmus Medical Center | 1 |
| Cairo University | 1 |
By country register
| Register | Trials | Recruiting |
|---|---|---|
| Clinical trials in Netherlands | 1 | 1 |
| Clinical trials in Belgium | 1 | 1 |
| Clinical trials in Canada | 1 | 1 |
| Clinical trials in Egypt | 1 | 1 |
A trial with sites in more than one country appears in each of those registers.
Questions about Doxapram trials
How many clinical trials are testing Doxapram?
2 current trials in our Netherlands, Belgium, Canada and Egypt registers name Doxapram as a drug or biological intervention, as of the registry sync on 10 November 2026. Completed and withdrawn studies are not counted.
Are Doxapram trials recruiting patients?
Yes. 2 of the 2 trials are recruiting: 1 with sites in Netherlands, 1 with sites in Belgium, 1 with sites in Canada and 1 with sites in Egypt. Eligibility and site contacts are on each trial's record. Only the study team can confirm whether a patient is eligible.
Who sponsors Doxapram clinical trials?
Erasmus Medical Center (1) and Cairo University (1). The number in brackets is how many trials each organisation leads.
Is Doxapram licensed in Ireland?
Yes. The HPRA medicines list includes 2 single-substance products containing Doxapram, for example Doxapram Hydrochloride 20mg/ml Solution for Injection (MercuryPharm Ltd). A licence does not mean a product is currently marketed or reimbursed; see each product's record.
Is there a Doxapram shortage?
Not in the lists we track: Doxapram has no entry in the EMA, FDA or German BfArM shortage registers as of their latest sync.
Where does this information come from?
Every trial, status, phase and sponsor on this page is copied from public ClinicalTrials.gov records by a daily sync. Nothing here describes how Doxapram works or whether it is effective, and it is not medical advice.
How this page is built
Everything on this page is copied from public ClinicalTrials.gov registry records — it is not written from memory, and nothing here describes how Doxapram works or whether it is effective. Each trial links to its own record so you can check it yourself.
- ClinicalTrials.gov (U.S. National Library of Medicine) ↗ Trial IDs, titles, intervention names and synonyms, phase, overall status, lead sponsor and conditions for every trial on this page
This page is built automatically: a daily sync job reads the registry records behind our country trial registers, collects every trial that lists Doxapram (or a registered synonym) as a drug or biological intervention, and tabulates the registry fields directly. Placebos and generic comparators are excluded. There is no AI drafting and no per-compound editorial pass, and the page has not been clinically reviewed. The “last verified” date above is the timestamp of that sync, not a review date. Our general editorial approach is described in our editorial standards and corrections policy. The ClinicalTrials.gov data on this page was last retrieved on 10 Nov 2026. How every register is built: methodology · fixes we have made: corrections log.