Ireland
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Recruiting Phase 4

Tirbanibulin for Pediatric Warts

NCT06791525 · tracked via the Priya Life Science USA tracker
Sponsor
The Skin Center Dermatology Group
Phase
Phase 4
Started
2025-05-01
Last updated
2026-04-23

Condition(s) studied

Warts Hand

Investigational drug(s) / intervention(s)

Tirbanibulin ointment 1% →

Tirbanibulin ointment 1%: Topical application

Study summary

Warts are common, benign skin lesions caused by the human papillomavirus (HPV). Treatment is challenging, particularly in the pediatric population, where standard modalities such as cryotherapy and intralesional immunotherapy are poorly tolerated. Existing topical treatments, such as imiquimod and 5-fluorouracil, have low efficacy and require prolonged use. Case reports suggest tirbanibulin ointment may provide an effective and well-tolerated alternative for pediatric warts. This study will evaluate the efficacy and safety of tirbanibulin ointment in treating pediatric hand warts.

Eligibility

Sex
ALL
Min age
8 Years
Max age
18 Years
Healthy volunteers
No
Inclusion Criteria: 1. Age 8-18 2. Subject and their legally authorized representative must be able to understand and be willing to adhere to all protocol requirements and voluntarily sign and date informed consent and assent for minors. 3. Subject is judged to be in good health as determined by the Principal Investigator, based upon the results of the screening assessments and medical history. 4. Diagnosis of warts on the hands 5. Wart count on the hands and 3-10 Exclusion Criteria: 1. Wart duration \>2 years. 2. More than 10 warts in non-hand areas. 3. Total wart surface area on the hands bigger than 100 cm2 4. Prior treatment failure with the following modalities: 1\. intralesional immunotherapy 2. intralesional bleomycin, 5-fluorouracil, methotrexate 3. intralesional cidofovir 5. Any over the counter, prescription topical, or in-office procedural wart treatment within 6 weeks of baseline (Day 1) 6. Known immuno-suppressed state due to disease or medication, medical treatment o 7. Known allergy to any component of the IP 8. Any conditions that, in the Principal Investigator's opinion, may interfere with the course of the study

Primary outcome measure(s)

  • Resolution — 2 months aftre completion of 4 or less treatment cycles
    Ful resolution of treated lesions

Trial sites (1)

FacilityCityRegionStatus
The Skin Center Dermatology Group New City New York Recruiting

More The Skin Center Dermatology Group trials in the USA

Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT06791525 on ClinicalTrials.gov ↗ ← All trials in the USA