This is a multicenter, non-interventional study to observe the natural progression of the disease and to study the prevalence of pre-existing antibodies to AAV9 used for gene therapy in a population of patients with PKP2 gene-associated ARVC. Participation from all patients is encouraged regardless of interest in or eligibility for gene therapy.
| Facility | City | Region | Status |
|---|---|---|---|
| University of California San Francisco | San Francisco | California | Recruiting |
| University of Colorado, Denver | Aurora | Colorado | Recruiting |
| John Hopkins University School of Medicine | Baltimore | Maryland | Recruiting |
| Brigham and Women's Hospital | Boston | Massachusetts | Recruiting |
| Mayo Clinic | Rochester | Minnesota | Recruiting |
| New York University | New York | New York | Recruiting |
| Cleveland Clinic | Cleveland | Ohio | Recruiting |
| Medical University of South Carolina | Charleston | South Carolina | Recruiting |
| Hopital Louis Pradel | Bron | France | Recruiting |
| Nantes University Hospital | Nantes | France | Recruiting |
| Pitié-Salpêtrière Hospital | Paris | France | Recruiting |
| Hôpital Haut-Lévêque | Pessac | France | Recruiting |
| University Hospital Muenster | Münster | Germany | Recruiting |
| Wuerzburg University Hospital | Würzburg | Germany | Recruiting |
| Centro Cardiologico Monzino | Milan | Italy | Recruiting |
| Istituti Clinici Scientifici Maugeri SpA | Pavia | Italy | Recruiting |
| Skåne University Hospital | Malmö | Sweden | Recruiting |
| The Queen Elizabeth Hospital | Glasgow | United Kingdom | Recruiting |
| Barts & The London Health NHS Trust | London | United Kingdom | Recruiting |
| St. George's University Hospitals NHS Foundation Trust | London | United Kingdom | Recruiting |
| Royal Brompton & Harefield NHS Foundation Trust | London | United Kingdom | Recruiting |
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT06311708 on ClinicalTrials.gov ↗ ← All trials in the USA