An Open-label Study of XEN1101 in Epilepsy
Condition(s) studied
Study summary
This study will evaluate the long term safety, tolerability, pharmacokinetics (PK), and efficacy of XEN1101 in subjects with Focal Onset Seizures (FOS) or Primary Generalized Tonic-Clonic Seizures (PGTCS) for the treatment of seizures for up to 6 years.
Eligibility
Primary outcome measure(s)
- The adverse events — From the start of treatment in the open-label extension (OLE) study through 8 weeks after the last dose.
To assess the safety and tolerability of XEN1101
Trial sites (153)
| Facility | City | Region | Status |
|---|---|---|---|
| Xenoscience | Phoenix | Arizona | |
| University of Arizona - Health Sciences | Tucson | Arizona | |
| Clinical Trials, Inc | Little Rock | Arkansas | |
| Brain Science Research Institute | Los Angeles | California | |
| UC Irvine Health | Orange | California | |
| University of California, Davis Clinical & Translational Science Center Clinical Research (CCRC) | Sacramento | California | |
| University of Colorado Hospital Anschutz Outpatient Pavilion | Aurora | Colorado | |
| Mayo Clinic Florida | Jacksonville | Florida | |
| Serenity Research Center, LLC | Miami | Florida | |
| Research Institute of Orlando, LLC | Orlando | Florida | |
| Panhandle Research & Medical Clinic | Pensacola | Florida | |
| University of South Florida | Tampa | Florida | |
| Encore Medical Research of Weston, LLC | Weston | Florida | |
| Hawaii Pacific Neuroscience | Honolulu | Hawaii | |
| Consultants in Epilepsy and Neurology | Boise | Idaho | |
| Indiana University School of Medicine | Indianapolis | Indiana | |
| The University of Kansas Medical Center | Kansas City | Kansas | |
| Bluegrass Epilepsy Research, LLC | Lexington | Kentucky | |
| Kentucky Clinic | Lexington | Kentucky | |
| MMP Neurology | Scarborough | Maine | |
| University of Maryland Medical Center | Baltimore | Maryland | |
| Mid-Atlantic Epilepsy and Sleep Center | Bethesda | Maryland | |
| Brigham and Women's Hospital | Boston | Massachusetts | |
| UMass Chan Medical School | Worcester | Massachusetts | |
| University of Michigan Hospitals | Ann Arbor | Michigan | |
| Wayne State University | Detroit | Michigan | |
| Michigan State University | East Lansing | Michigan | |
| Cornwell Health (Spectrum Health Hospitals) | Grand Rapids | Michigan | |
| Minneapolis Clinic of Neurology | Burnsville | Minnesota | |
| Saint Louis University Medical School | St Louis | Missouri | |
| Northeast Epilepsy Group | Hackensack | New Jersey | |
| Dent Neurosciences Research Center | Buffalo | New York | |
| New York University Comprehensive Epilepsy Center | New York | New York | |
| Mount Sinai Health | New York | New York | |
| SUNY Upstate Medical University | Syracuse | New York | |
| Montefiiore Medical Center | The Bronx | New York | |
| Onsite Clinical Solutions | Charlotte | North Carolina | |
| Duke University | Durham | North Carolina | |
| Meridian Clinical Research, LLC | Raleigh | North Carolina | |
| Summa Health | Akron | Ohio |
+ 113 more sites — see the full list on the official registry below.
More Xenon Pharmaceuticals Inc. trials in the USA
Other trials for the same condition
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT05718817 on ClinicalTrials.gov ↗ ← All trials in the USA