Bridge-Enhanced ACL Repair-Safety Study (BEAR Trial)

Inclusion Criteria: * Complete ACL tear, confirmed by MRI * Time from injury to screening must be less than or equal to 90 days * ACL tissue present on pre-operative MRI Exclusion Criteria (before surgery): * Prior surgery on affected knee * History of prior infection in affected knee * Regular use of tobacco or nicotine in any form * Use of corticosteroid within last 6 months * Ever underwent chemotherapy treatment * History of sickle cell disease * History of anaphylaxis * Any condition that could affect healing (Diabetes, inflammatory arthritis, etc) * Diagnosis of posterolateral corner injury (LCL complete tear, Biceps femoris tendon avulsion, tear of the arcuate ligament, tear of the popliteus ligament) * Diagnosis of Grade III medial collateral ligament injury * Diagnosis of complete patellar dislocation Exclusion Criteria (during surgery): * ACL deemed normal on arthroscopic inspection * Time from injury to surgery is greater than 90 days (for Comparator group) and greater than 30 days (for Experimental group) * Experimental Group: Less than 50 percent of ACL remaining * Displaced bucket handle meniscal injury requiring repair * Diagnosis of full-thickness chondral injury on either condyle * Grade III medial collateral ligament injury