Haemdall: Developing a Quantitative MRI Biomarker of Infratentorial Superficial Siderosis of the Central Nervous System
Condition(s) studied
Study summary
Haemdall: Using Medical Imaging to measure Brain Iron in Superficial Siderosis.
This study is looking at a new way of using MRI scans to potentially measure the amount of iron on the surface of the brain. Iron build up in the brain is linked to how superficial siderosis develops. The study will also aim to see if there is a connection between the amount of iron in the brain and common superficial siderosis symptoms. Clinical tests will be used to measure symptoms including tests to measure your hearing, walking \& balance and participants' ability to remember, think and understand.
Eligibility
Primary outcome measure(s)
- To evaluate the association and clinical relevance of with markers of neurodegeneration and clinical assessments — through study completion, an average of 1 year
1. Correlation between magnetic susceptibility assessed by QSM and brain cognitive function by MoCA. 2. Correlations between magnetic susceptibility assessed by QSM and: a) markers of neurodegeneration; and b) clinical assessment outcomes (auditory, balance, gait, cognitive)
Trial sites (1)
| Facility | City | Region | Status |
|---|---|---|---|
| Perspectum | Oxford | United Kingdom | Recruiting |
More Perspectum trials in the UK
This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.
View NCT07098650 on ClinicalTrials.gov ↗ ← All trials in the UK