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Starting soon Observational

Anticipated Stigma, Illness Identity, and Quality of Life in Male Hypogonadism

NCT07752511 · tracked via the Priya Life Science Turkey tracker
Phase
Observational
Started
2026-10-01
Last updated
2026-08-07

Condition(s) studied

Hypogonadism, MaleEndocrine DiseaseHypertension

Study summary

This study aims to systematically compare the levels of anticipated illness stigma and illness identity among men diagnosed with hypogonadism to those of men with other chronic endocrine conditions (e.g., diabetes mellitus, hypothyroidism, and hypertension). Furthermore, it examines whether these psychosocial variables predict quality-of-life deterioration specifically within the hypogonadism cohort.

Eligibility

Sex
MALE
Min age
18 Years
Max age
—
Healthy volunteers
No
Inclusion Criteria: Cases: * Male, aged 18 years or older. * Biochemically confirmed hypogonadism (total testosterone \< 300 ng/dL with at least one clinical symptom). * Regular follow-up at the endocrinology outpatient clinic. * Fluent in reading and understanding Turkish. * Signed informed consent. Controls: * Male, aged 18 years or older. * Diagnosed with diabetes, hypertension, or hypothyroidism under regular endocrinology follow-up. * Total testosterone ≥ 300 ng/dL. * Age-matched to a participant in the case group (±5 years). * Fluent in reading and understanding Turkish. * Signed informed consent. Exclusion Criteria: * Active psychiatric diagnosis (e.g., active psychosis, bipolar disorder). * Chronic inflammatory or rheumatological diseases affecting body composition (e.g., chronic kidney disease, IBD, rheumatoid arthritis, SLE, ankylosing spondylitis). * Uncontrolled co-existing endocrine conditions or severe complications (e.g., HbA1c \> 8.0%, diabetic neuropathy/nephropathy/retinopathy, non-euthyroid state). * Cognitive impairment or dementia precluding questionnaire completion. * Klinefelter syndrome. * Literacy limitations preventing completion of self-report measures. * Additional control exclusion: Diagnosis or clinical suspicion of hypogonadism.

Primary outcome measure(s)

  • Chronic Illness Anticipated Stigma Scale (CIASS) Score — Baseline (Single session, day 1)
    Measures anticipated stigma across three subscales (friends/family, work, healthcare workers) on a 5-point Likert scale.
  • Brief Illness Perception Questionnaire (Brief IPQ) Score — Baseline (Single session, day 1)
    Assesses cognitive and emotional representations of illness. Higher total scores indicate a more threatening illness perception.

Trial sites (2)

FacilityCityRegionStatus
Bingöl University Faculty of Physical Therapy and Rehabilitation Bingoel Turkey (Türkiye)
Malatya Training and Research Hospital Malatya Turkey (Türkiye)
Official registry record

This page summarises publicly available registry data for informational purposes — not medical advice. Eligibility is determined by each study team; patients should discuss participation with their clinician.

View NCT07752511 on ClinicalTrials.gov ↗ ← All trials in Turkey